乳痛宁对大鼠乳腺增生病模型的作用_张科伟.pdfVIP

32 　3 　　　　　　(　　 ) Vo l. 32 N o. 3 2006 5 J ournal of Jilin U niversity (M edicine Editio n) M ay 2006 413 　　[] 　167-1 5 87 Ⅹ(2006)03-041-3 0 3 1 1 2 1 1 1 * 张科伟 , 付　彤 , 任立群 , 李嗣杰, 孙淑滨 , 范志民 (1. , 13002 1; 2. , 130021) [　] 　:。 :W istar 50 , 、 、 、 , 10 , , , 2 , , , 、 。:、 、 (P0.05), (P0.05), 2 (P0.05), , (P0.01), 、 。 :, , 。 [] 　 ;;;;, [] 　R-332;　R655.8　　[] 　A Effects of Rutongning on hyperplasia of mammary glands in rats 1 1 2 1 1 1 * ZH A NG K-e w ei , F U T ong , REN L-i qun , LI S-i j ie , SU N Shu-bin , F AN Zh-i min (1. Depa rtment of T ho racic Surge ry, Fir st Ho spital, Jilin Univ ersity, Chang chun 130021, China; 2 . Depar tme nt o f Patholog y, Institute o f Fr ontier M edical Sciences, Jilin Unive rsity, Changchun 130021, China) Abstract:Object ive 　T o discu ss the eff ects and mechanism o f Ruto ng ning cap sule on hy per plasia of mammary glands in rats . Methods　50 f emale Wista r rats w itho ut preg nancy w er e r andomly divided into nor mal g roup, mo del gr oup, low do sag e g roup, middle dosag e gr oup and high dosage g ro up (n=10). Estradiol and pr oge ster one w e re used to induce hy per plasia models o f mammary g lands in rats . T he rats w ith hy per plasia of mamma ry glands w e re administer ed by gav age w ith Rutongning. T he diameter o f the second tw in nipples of the rats w a s measur ed and the structur e of the mammary gland tissue w as o bserv ed. T he level o f ho rmone in blood w a