肥大细胞的研究进展.pdfVIP

# 104# 2011 42 2 肖淑华 刘阳阳 魏连海 郭 义v (, 300193) 肥大细胞作为主要的免疫细胞之一, 不仅参与机体过敏炎症, 组织损伤修复免疫等反 , 还与很多生理病理过程有关它的分化成熟激活和介质的释放都受到严格的调控对肥大细胞 的深入研究既可以使我们更加透彻地了解过敏炎症和免疫性疾病的机理, 也可以为此类疾病的预 防和治疗提供有价值的参考和借鉴 肥大细胞; 调控; 激活; 功能 Advancem ent in R esearches ofM as t Cell X IAO Shu-Hua, LIU Y ang-Y ang, WE I L ian-H ai, GUO Y i (C enter of Exp erim ental A cup unc ture, T ianj in Un iversity of Trad itional Ch inese M ed ic ine, T ianj in 300193, Ch ina) Abs tract M a t cell a the body m ain mi m une cell , not only involved in allerg ic, in flamm atory re- pon e, but al o related to a lot of phy iolog ical and patholog ical proce e . It differentiation, m atura- tion, activation and m edia relea e are in trict regulation and control. The in-depth tudy ofm a t cell not on ly allow u to under tand them echan im of allergy, inflamm ation and au tomi m une di ea e m ore thor- oughly, bu t al o prov ide u om e valuable reference about the prevention and treatm ent of uch di ea e . K ey w ord s m a t cell; regu lation; activation; function + (m a t cell) CD34 3( IL-3)IL-13IL-9 , m a t cell , , , , T ach ibana , ( 2008) , ( PPAR ), , IL-4 , [ 1] Fung( 2009) , ()