猪去氧胆酸的纯化工艺.pdfVIP

2006, 21( 4): 360~ 362 W C J P S PHC PHC M M 1 3 , M M 1 3 , M2 PHC 050mg : - 1 [ 1] , , . m l , , - 1 [ J]. , 2004, 19( 4): 702- 703. 050mgm l , - 1 [ 2] . [M ]. 3. : 0. 29 0. 58 mgm l , 2001. 1376. - 1 PHC 050mgm l 1~ 30m in [ 3] arnes PJ. The role of anticholinergics in chronic obstructive pul - 1 , , 1020 mgm l monary disease[ J]. Am JM ed, 2004, 117( Suppl 12A): 24S- 60 m in, 32S. - 1 : 2006- 03 050mgm l 1~ 30 m in PHC, * , , , , (, 610041) : , : ; ; ; : 282. 74 : A : 1006- 0103( 2006)04- 0360- 03 The purified process of hyodeoxycholic acid * SU Hong, YE Li- m ing, YANG Y i- xi, LIU M ing- dong, FAN Ju- zheng (West China S chool of Pharmacy, S ichuan University, Chengdu 610041, China) Abstract: OBJECTIVE To investigate the mi purities of the hyodeoxycholic acid and its purification.METHODS Recrystallization and column chromatography w ere used to get purer hyodeoxycholic acid and some other components. ESULTSAND CONCLUSION Hyodeoxycholic acidw as purified by recrystallization and column chromatography. The major mi purityw as confirmed as biliary acid. K ey words: Hyodeoxycholic acid; Purification; Structure identification; Impurity CLC number: 282. 74 Document code: A Article ID: 1006- 0103(