GADAb、ICA和IAA联合检测与LADA早期诊断.pdfVIP

18 塞筮医堂垫Q墨生箜堑鲞蔓!翅 范爱红徐卓华 陈 燕 叶山东 [摘要] 和体重，计算BMI。结果DM组抗体总阳性率高于对照组；与肥胖及超重组(BMI23 kg／m2)相比，非肥胖组(BMI≤ 23 临床初步诊断的2一DM者胰岛p kg／m2)抗体阳性率明显增高，抗体阳性组胰岛素和C肽水平低于阴性组。结论 细胞自身抗体的检测，有助于LADA的早期诊断和其G细胞功能的保护。 [关键词]成人隐匿性自身免疫性糖尿病；自身抗体；诊断 IAA LADA ofGADAb，ICAand measurementsforthe of Sigmfie锄ee earlydiagnosis al FanAihong，‰Zhuohua，ChenYan，et AnhuiProvincialEndocrine 230001 Hospital Laboratory，Hefei To I ADA andIAAmeasurement，thenthefunctionof [Abstract]ObjectivediagnoseearlybyGADAb，ICA protect isletcell．Methods andIAAweremeasuredin130 2diabeticsclinicalcharacteristic p GADAb，ICA newlydiagnosedtype by and50normal ELISAor insulinand insulinandC—Palsoweremeasuredinall subjectsby RIA，Fasting C—P，postprandial and wererecordedfor BMI．ResultsThe ratesofauto—antibodiesindia— weightheight calculating positive participants，Body beticswere thanthosein ratesofauto—antibodiesinfator diabetic higher controls。Thepositive overweight increased withnon—fat levelsoffastinsulinand in— diabetic C—P，postprandial Kg／n12)weresignificantlycompared group；The in werelowerthanthosein sulinandC—P diabetic positiveauto—antibodies negative patients诵th auto—antibodypatients． ConclusionGADAb．ICAandIAAmeasurementshavevaluefor