Radix Saposhnikovia extract suppresses mouse allergic contact dermatitis by regulating dendritic-cell-activated Th1 cells》.pdf

ARTICLE IN PRESS JID: PHYMED [m5G;October 6, 2015;11:30] Phytomedicine xxx (2015) xxx–xxx Contents lists available at ScienceDirect Phytomedicine journal homepage: /locate/phymed Radix Saposhnikovia extract suppresses mouse allergic contact dermatitis by regulating dendritic-cell-activated Th1 cells Q1 a a a a b c a,∗ Xi Yu , Yan Niu , Jie Zheng , Hailiang Liu , Guorong Jiang , Junhao Chen , Min Hong aJiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Jiangsu Key Laboratory of Pediatric Respiratory Disease, Nanjing University of Chinese Medicine, Nanjing 210023, China b Suzhou Hospital of Traditional Chinese Medicine, Suzhou 215000, China c Center of Clinical Laboratory, Gulou Hospital, Nanjing, PR China a r t i c l e i n f o a b s t r a c t Article history: Background: Radix Saposhnikovia (RS), called “Fangfeng” in China, is commonly used in Chinese medicinal Received 9 March 2015 formulae to treat allergic and inflammatory diseases. However, the underlying mechanisms of RS in amelio- Revised