Recent advances in cell membrane chromatography for traditional Chinese medicines analysis》.pdf

Journal of Pharmaceutical and Biomedical Analysis 101 (2014) 141–150 Contents lists available at ScienceDirect Journal of Pharmaceutical and Biomedical Analysis j o u r n a l h o me p ag e: w w w. elsev /locate/jpba Recent advances in cell membrane chromatography for traditional Chinese medicines analysis Xiaofang Hou, Sicen Wang, Tao Zhang, Jing Ma, Jie Zhang, Yanmin Zhang, Wen Lu, Huaizhen He, Langchong He ∗ Xi’an Jiaotong University Health Science Center, Yanta West Road, Xi’an 710061, Shaanxi, China a r t i c l e i n f o a b s t r a c t Article history: Traditional Chinese medicines (TCMs) have been used for preventative care for thousands of years. The Received 7 March 2014 active components are the basis for the pharmacodynamics of TCMs, and they can be an important source Received in revised form 7 May 2014 of lead compounds. As a bioaffinity chromatography technique, cell membrane chromatography (CMC) Accepted 9 May 2014 has been developed for almost 20 years since 1996. It has been proven to be a useful method for studying Available online 23 May 2014 drug–receptor interactions and screening active components from medicinal herbs. In our review in 2007 (Drug Discov. Ther., 1 (2007) 104–107), the preparation, identification, evaluation, and preliminary Keywords: applications of CMC stationary phases were presented. In this article, we briefly review some of the latest Cell membrane chromatography Traditional Chinese medicines