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《Pristimerin enhances recombinant adeno-associated virus vector-mediated transgene expression in human cell lines in vitro and murine hepatocytes in vivo.》.pdf

《Pristimerin enhances recombinant adeno-associated virus vector-mediated transgene expression in human cell lines in vitro and murine hepatocytes in vivo.》.pdf

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《Pristimerin enhances recombinant adeno-associated virus vector-mediated transgene expression in human cell lines in vitro and murine hepatocytes in vivo.》.pdf

JournalHomepage: wwwjcimjourna1.corn/jim www.elsevier.com/locate/issn Availablealsoonlineatwww.sciencedirect.com. Copyright@2014.JournalofIntegrativeMedicineEditorialoffice. E-editionpublishedbyElsevier(Singapore)PteLtd.Allrightsreserved ≮j ● Pristimerinenhancesrecombinantadeno—associated ressioninhuman ● ● ■ ■ ■ 0 一 ■ ■ 0 一 一 ■ ■ ce¨llnesin vitroandm U¨nehepatocytes,n Wvo Li.naWang’I213,YuanWang1,2,3,4YuanLu,zi-feiYin’,Yuan-huiZhang’,,。,George Aslanidi, ArunSrivastavaI3I61 Chang-quanLing’ ChenLing,。 , , 1.ChanghaiHospitalofTraditionalChineseMedicine.SecondM_litaryMedicalUniversity.Shanghai 200433.China 2.DivisionofCellularandMolecularTherapy.DepartmentofPediatrics,UniversityofFloridaCollegeof Medicine,Gainesville Florida32611。USA 3.PowelIGeneTherapyCenter,UniversityofFloridaCollegeofMedicine,Gainesville,Florida32611,USA 4.ShanghaiUniversityofTraditionalChineseMedicine.Shanghai201203.China 5.DepartmentofOrthopaedicsandRehabiIitati0n,UniversityofFloridaCollegeofMedicine,Gainesville, Florida32611.USA 6.DepartmentofMolecularGeneticsandMicrobiology,UniversityofFloridaCollegeofMedicine,Gainesville, Florida32611.USA 7.Geneticslnstitute,UniversityofFloridaCollegeofMedicine,Gainesville.Florida32611,USA 8.ShandsCancerCenter,UniversityofFloridaCollegeofMedicine,Gainesville,Florida32611,USA OBJECTlVE:lnthepresentstudy.we systemicallyevaluated theab_lity oftwobioactive compoundsfrOm traditionaIChinesemedicine,celastrolandpristimerin.toenhancerecombinant adeno.associatedvirus(rAAV)serotypevector-mediatedtransgeneexpressionbothinhuman celllinesinvitr

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