基于氨基酸的苯并咪唑合成研究进展有机化学.pdfVIP

DOI: 10.6023/cjoc201301064 综述与进展 有机化学 Chinese Journal of Organic Chemistry REVIEW 基于氨基酸的苯并咪唑合成研究进展 彭 湃a 熊金锋a 李 豹b 莫广珍a 陈任宏c 汪朝阳*,a (a 华南师范大学化学与环境学院 教育部环境理论化学重点实验室 广州 510006) (b 华南理工大学化工学院 广州 510630) (c 广东食品药品职业学院 广州 510520) 摘要 苯并咪唑类化合物在药物化学、生物化学、配位化学以及催化、分子识别、阻燃等领域具有重要应用. 氨基酸 类化合物是一类来源广泛的功能性合成子, 因此近年来基于氨基酸的苯并咪唑合成与功能改性研究受到人们的广泛关 注. 综述了以各种天然与非天然氨基酸为原料, 以溶液法、微波法、固相法等合成技术合成与改性苯并咪唑的新进展. 关键词 苯并咪唑; 氨基酸; 合成子; 合成; 进展 Progress in the Synthesis of Benzimidazoles Based on Amino Acids Peng, Paia Xiong, Jinfenga Li, Baob Mo, Guangzhena Chen, Renhongc Wang, Zhaoyang*,a a ( Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, School of Chemistry and Environment, South China Normal University, Guangzhou 510006) b ( School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510630) c ( Guangdong Food and Drug Vocational College, Guangzhou 510520) Abstract Benzimidazoles have important applications in the fields of medicinal chemistry, biochemistry, coordination chemistry, catalysis, molecular recognization, and flame retardant. Amino acids as a kind of functional synthons have wide sources, more and more attentions have been attached to the researches on the synthesis of benzimidazoles and their functional modification based on