基于氨硼烷的直接转移氢化反应研究进展有机化学.pdfVIP

DOI: 10.6023/cjoc201412057 综述与进展 有机化学 Chinese Journal of Organic Chemistry REVIEW 基于氨硼烷的直接转移氢化反应研究进展 阳香华* 谢珍茗 何 军 余 林* (a 广东工业大学轻工化工学院 广州 510006) 摘要 直接转移氢化反应是指氢原子在没有催化剂参与的情况下从氢供体转移到氢受体的过程——即所谓不含金属 的反应. 该过程是机理研究中理想的基本步骤, 却通常因反应能垒太高而鲜少报道. 然而, 理论和实验研究都表明, 提 高底物的极性可有效降低反应能垒, 意味着极性的氢供体和氢受体直接很可能发生这类反应. 氨硼烷是一种含氢量很 高的知名化学储氢材料, 同时, 它也是一种同时含有正、负电性氢原子的理想极性氢供体. 事实上, 以氨硼烷为极性氢 供体, 亚胺、极化烯烃以及醛酮等为极性氢受体, 直接转移氢化反应能在温和条件下发生. 主要对这些反应的底物范围 以及机理上的异同进行了综述. 关键词 氨硼烷; 直接转移氢化反应; 反应机理; 绿色化学 Research Progress on Ammonia-Borane Based Direct Transfer Hydrogenation Reactions Yang, Xianghua* Xie, Zhenming He, Jun Yu, Lin* (School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006) Abstract Direct transfer hydrogenation reaction is a H transfer process from a hydrogen donor to a hydrogen acceptor without the presence of a catalyst——the so-called metal-free reaction. It’s an idea elementary process for mechanistic study, but was rarely reported due to very high energy barriers. However, it is revealed both theoretically and experimentally that increase in polarity of the substrates can efficiently lower the energy barrier, meaning that polar hydrogen donor and hydrogen acceptors might make such reactions happen. Ammonia borane is well-known as a chemical hydrogen storage material with very high H content. In the meanwhile, it ’s an ideal