氯磷灰石负载金属卤化物催化芳香化合物的Friedel-Crafts苄基化反应研究有机化学.pdfVIP

2011 年第 31 卷 有 机 化 学 Vol. 31, 2011 第 3 期, 392～396 Chinese Journal of Organic Chemistry No. 3, 392～396 ·研究简报· 氯磷灰石负载金属卤化物催化芳香化合物的 Friedel-Crafts 苄基化反应研究 未本美* 张智勇 戴志群 张开诚 (武汉工业学院化学与环境工程学院 武汉 430023) 摘要 以氯磷灰石为载体, 采用水热法制备了氯磷灰石负载金属卤化物固体酸催化剂, 通过 IR, XRD 对载体和催化剂 的结构进行了表征. 研究了催化剂对芳香化合物与苄基氯、苄基溴和苄基醇的 Friedel-Crafts 烷基化反应. 结果表明, 溴 化锌负载氯磷灰石催化剂的活性最高, 而且催化剂易回收和重复使用, 催化剂重复使用 5 次活性没有明显降低. 关键词 氯磷灰石; 金属卤化物; Friedel-Crafts 苄基化反应; 芳香化合物; 催化 Friedel-Crafts Benzylation of Aromatic Compounds Catalyzed by Chloroapatite Supported Metal Halides Wei, Benmei* Zhang, Zhiyong Dai, Zhiqun Zhang, Kaicheng (School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan 430023) Abstract The chloroapatite (ClAP) supported metal halides catalysts were prepared by the hydrothermal method using ClAP as the support. The catalysts were characterized by the techniques such as IR and XRD. Friedel-Crafts benzylation reactions of aromatic compounds with benzyl chlorides, benzyl bromides and benzyl alcohols were investigated. The experiments indicated that the best results were obtained with ClAP supported ZnBr2 . Furthermore, the catalyst could be easily recovered by simple method and reused for at least 5 times without losing its activities. Keywords chloroapatite; metal halide; Friedel-Crafts benzylation; aromatic compound; catalyzed 芳香化合物的 Friedel-Crafts 烷基化反应[1～3]是有机 好和可重复使用等优点, 但一般载体制备工艺复杂且价 合成中构建 C— C 键的重要方法之一 . 通常 Friedel- 格昂贵. Crafts 烷基化反应需要大量的 Lewis