Hydronephrosis Resulting from Bilateral Ureteral Stenosis A Late Complication of Polyoma BK Virus Cystitis.pdfVIP

Hindawi Publishing Corporation Journal of Transplantation Volume 2010, Article ID 297358, 6 pages doi:10.1155/2010/297358 Case Report Hydronephrosis Resulting from Bilateral Ureteral Stenosis: A Late Complication of Polyoma BK Virus Cystitis? N. Basara,1 F.-M. Rasche,2 T. Schwalenberg,3 C. Wickenhauser,4 M. Maier,5 J. Ivovic,6 D. Niederwieser,1 and T. H. Lindner2 1 Department of Hematology/Oncology and Hemostaseology, University Hospital Leipzig, Johannisallee 32a, 04103 Leipzig, Germany 2 Department of Nephrology, University Hospital Leipzig, 04103 Leipzig, Germany 3 Department of Urology, University Hospital Leipzig, 04103 Leipzig, Germany 4 Institute of Pathology, Faculty of Medicine, University of Leipzig, Leipzig, Germany 5 Institute of Virology, University Hospital Leipzig, 04103 Leipzig, Germany 6 Department of Urology, General Hospital, Bar, Montenegro Correspondence should be addressed to N. Basara, nadezda.basara@uniklinik-leipzig.de Received 18 May 2010; Revised 15 August 2010; Accepted 7 September 2010 Academic Editor: O. Ringden Copyright © 2010 N. Basara et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. We report here a case of acute lymphoblastic leukemia in remission presenting a late-onset bilateral hydronephrosis probably due to polyoma BK virus-induced proliferation of bladder endothelium on both ostii. The diagnosis was made virologically by BK virus Polymerase Chain Reaction (PCR) detection in the absence of any other bladder disease. Awareness of this late complication is necessary not only in patients after renal transplantation but also in patients after hematopoiet