乳腺增生病、癌病变和乳腺癌中医证型与Ki-67、Bcl-2表达差异的相关性研究.pdfVIP

Mammary glands,precancerous lesions,breast cancer,Ki-67,Bcl-2 and relationship with TCM Speciality：Surgery of TCM Author ：Li Zhenzhen Tutor ：Prof. Yang Yi Abstract Objective：The study of pathology diagnosis for breast hyperplasia, precancerous lesions, breast cancer cases were Ki67, bcl-2 research and analysis of traditional Chinese medicine syndromes, and to study the correlation between the two, on TCM microscopic, quantification of exploration, for precancerous lesions of breast carcinoma provide theoretical basis for the treatment of traditional Chinese and Western medicine. Methods ：Collection of the Affiliated Hospital of Shandong University of Traditional Chinese Medicine of breast and thyroid surgery from April to 2010 2007 and June were pathologically diagnosed as benign breast hyperplasia, breast cancer, precancerous lesions in female patients with 30 cases in each case, the syndrome differentiation for stagnation of phlegm syndrome:, phlegm-blood stasis, poison knot to phlegm and blood stasis syndromes 3. The collection of information, using immunohistochemical method, detection of 90 cases of Ki-67, Bcl-2 expression, and analyzes the relationship between TCM syndrome type and. Using the SPSS19.0 data package was used for statistical processing. Result: ①The stagnation of phlegm, phlegm, Phlegm Stasis Toxin knot 3 syndrome in the mammary glands, precancerous lesions, the distribution of breast cancer had significant difference ( P 0.05 ). ②The Ki67, Bcl-2 in the mammary glands, precancerous lesion and breast carcinoma with positive expression of TCM Different no significant correlation ( P 0.05 ). ③The expression of Ki-67 in breast hyperplasia to premali