中药糖益康对葡糖耐量减低患者的临床干预研究.pdfVIP

The Clinical Intervention Study of Herbal Medicine TangYiKang on subjects with impaired glucose tolerance Specialty: Internal Medicine of Traditional Chinese Medicine Author: Luo Dan Tutor: Prof.Xu Yunsheng Abstract Objective: Study the clinical curative effect of Chinese patent drug “Tang Yi Kang” using the method of Yiqi expectorant huoxue method with combined therapy of sex way on patients with IGT and discuss the intervention mechanism. Methods: Taking the method of randomized, placebo controlled prospective parallel, 120 patients with IGT were randomly divided into treatment group (n=60) and the control group (n=60).All the participants had received the knowledge about IGT and behavior intervention before the study.Treatment group received behavior intervention plus Tang Yi Kang treatment, and the control group received behavior intervention plus placebo treatment.Observation time last for 3 months, the main outcome measures are as follows: the clinical symptoms, the blood sugar, blood fat and glycated hemoglobin, insulin levels, body mass index, waist-hip ratios,inflammatory factor etc. Results: The blood sugar, blood fat and glycated hemoglobin, insulin levels, body mass index, waist-hip ratios,clinical symptom of the treatment group were obviously improved, which showed significant difference from the control group.During the tests adverse reactions did not appear. And in a year later’s follow-up, diabetes conversion rate of the treatment group is lower than those of the control group. Conclusion: The compound method of Yiqi expectorant huoxue method combined with behavior intervention has curative effect on IGT patients: decrease lipid sugar, reduce weight index and waist-hip ratios,improve the insulin resistan