环保灸盒与木制盒治疗功能性消化不良脾气虚证的临床疗效对照研究.pdfVIP

中文摘要 目的： （1）灸法对功能性消化不良脾气虚证患者的临床疗效评价；（2 ）比较环保灸盒 与木制灸盒治疗功能性消化不良脾气虚证的疗效差异； （3 ）探讨灸法治疗功 能性消化不良脾气虚证的机制；（4 ）比较环保灸盒不同于木制灸盒的特 点。 方法： 本研究采用随机、对照、单盲的临床试验方法，将符合纳入标准（功能性消化不 良脾气虚证）的96 例患者随机分为“环保灸盒”治疗组和“木制灸盒”对照组； 每组48 例，分别在中脘穴施灸。在治疗前后采用放射免疫法分别测定患者血清 胃泌素（GAS ）、免疫球蛋白IgG、白细胞介素2 （IL-2 ）的含量，并根据脾气 虚症状自评量表计算症状积分。 结果： （1）两组患者治疗后中医症状积分较治疗前明显降低，差异有统计学意义。（2 ） 经治疗后，功能性消化不良脾气虚证患者GAS 、IgG 含量均有不同程度的升高， P0.05,结果有统计学意义；各组治疗前后相比，IL-2 含量无明显变化。（3 ）环 保灸盒组与木制灸盒组之间症状积分、GAS 、IgG 含量无明显差异。 结论： （1）两种不同灸具均能有效地改善功能性消化不良脾气虚证患者的临床症状， 其作用机理可能与调节GAS 、IgG 有关；（2 ）两种不同灸具疗效无明显差异， 其中环保灸盒较木质灸盒具有阻燃、控温、少烟等优势。 关键词：环保灸盒 功能性消化不良 脾气虚证 ABSTRACT 【Object】 1 、To observe the clinical effect on treating spleen-Qi deficiency differentiation of functional dyspepsia (FD) by Moxibustion; 2 、Compare the effect of smokeless Moxibustion with wooden Moxibustion that treat the spleen-Qi deficiency differentiation of FD ; 3、 Discuss the mechanism of moxibustion that treat the spleen-Qi deficiency differentiation of FD;4、Compare the different features of smokeless Moxibustion with wooden Moxibustion. 【Method】The research used the random contrast and single -blind test .There are altogether 96 patients through the whole course of study. All cases were divided into two groups on the random:The comparision group which were treated by wooden Moxibustion on zhongwan point, and trerapeutic group which were treated by smokeless Moxibustion on zhongwan point. The clinical effect and the influence on PSQI and TCM symptom score were studied .Measuring the density in patients of gastrin (GAS) 、 immunoglobulinG(IgG) 、 interleukin-2(IL-2) By radioimmunoassav (RIA) and calculating fraction accord to Spleen-Qi Deficiency symptoms scale before and after treat