舒天宁颗粒治疗头痛风火痰瘀候优化方案研究.pdfVIP

Combined Therapy Research on Shutianning Granule Treating Migraine Speciality: Internal Medicine of TCM Author: Zhang Meng Tutor: Chief Physician Hu Zhiqiang Abstract Object:To observe the therapeutic effect of four treatments on the patients suffering from migraine of feng-huo-tan-yu type,which are combined by Shutianning Granule 3 g and Shutianning Granule 6 g composed or not composed of sibelium capsule 5 mg ,so as to find the best combined therapy of TCM on migraine of feng-huo-tan-yu type. Methods:80 patients with migraine of feng-huo-tan-yu type were randomly divided into Shutianning Granule 3 g group （the first group ）,Shutianning Granule 6 g group （the second group ）,Shutianning Granule 3 g and sibelium capsule 5 mg group （the third group ） and a group using both Shutianning Granule 6 g and sibelium capsule 5 mg （the forth group ）.All were treated for 28 days,and then being compared with the changes of headache index,accompany symptoms,SF-36,before and after treatment. Results:The statistic analysis revealed that the four groups are safe and effective to cure migraine of feng-huo-tan-yu type. The total effective rate of the four groups were 45%,70%,75% and 85%.There was quite significant difference between them （P0.01 ）. Sibelium capsule 5 mg and Shutianning Granule 6 g recipe improved headache index,and raising physical dimension,emotional dimension,social dimension,vitality dimension, general health dimension and bodily pain dimension of the SF-36 （P0.05 ）,while they have counterchange.All accompanied signs and symptoms were not improved in the general treatment group （P ＞0.05 ）,while other groups’ symptoms roups were improved （P0.05 ）.