补肾方药对老年性高血压病的临床干预及对性激素、rho激酶表达的影响.pdfVIP

Research on Invigorate kidney qi-deficiency intervention the level of sex hormones and Rho-kinase of Elderly female hypertensionby kidney deficiency syndrome Specialty: The Study of cardiovascular diseases, Internal medicine of TCM Author: Cai Xinrui Tutor: Professor Guo Weixing Abstract The study comes from the national natural science foundation “qi-deficiency intervention filling kidney deficiency elderly hypertension syndrome sex hormone receptor case kidney-qi express and control mechanism research”. Objective: To observed the invigorate kidney qi-deficiency intervention in elder female hypertensive patients with kidney deficiency syndrome level changes sex hormones and the level of Rho-kinase as well as the relationship between Rho-kinase and sex hormones. Methods: Collect age 65 to 75 in between with 1, 2 levels, with hypertension and kidney deficiency syndrome, the choice of chemical check all normal as normal controls the healthy elderly, 30 cases in each group above 2 groups controlled study. Detail the records of subjects’ blood pressure, clinical symptoms. Ria analysis by comparing three groups of participants differences in the levels of sex hormones (E2, T, FSH, LH) and analysis Rho-kinase with Enzyme immunoassay. Meet the criteria for the elderly hypertension patients with kidney deficiency syndrome, giving each 30 cases and the Yi shen Antihypertension Granule treatment for four weeks, patients were observed before and after treatment before the change and level of sex hormones as well as Rho-kinase clinical effect. Results: And the healthy female elderly and compared with patients who suffered inflammation card on, old hyperte