Ictaltachycardiaitsdiscriminatingpotentialbetweentemporalandextratemporalseizurefoci技术报告.docVIP

Ictal tachycardia: its discriminating potential between temporal and extratemporal seizure foci 发作性心动过速：颞叶及颞叶外致痫灶间的潜在差别 A wide variety of CNS lesions have been associated with changes in heart rate (HR). However, in epileptic patients their value to lateralize seizure onset remains controversial. This study aims to assess if HR changes associated with partial onset seizures could be useful in lateralizing seizure onset. 许多中枢神经系统病灶与心率变化相关。但是，在癫痫患者中，他们对于发作开始定侧价值仍然是有争议的。这研究旨在评估是否与部分发作开始相关的心率变化在发作开始定侧方面是有用的。 We analysed HR changes on 100 seizures from 38 consecutive patients (mean age: 27.5 years) admitted for video-EEG telemetry monitoring. We evaluated the R–R interval 30 seconds before the seizure onset and 10, 20 and 120 seconds after the onset. We assessed whether there was a correlation between HR changes and seizure type, left/right differences and different semiological components for each seizure. 我们分析了行视频脑电监测的38例连续患者（平均年龄：27.5）100次发作心率变化。我们评估了发作开始前30秒R-R间期以及发作开始后10秒、20秒以及120秒R-R间期。我们评估了心率变化与发作类型，左右侧差别，每次发作不同的症状学表现之间是否有相关性。 We recorded 100 seizures. Three non-lateralized seizures were excluded from the analysis; 63/97 (65%) had left hemisphere onset, mainly from the temporal lobe (57.7%). The mean baseline HR was 77 beats per minute Ictal tachycardia (HR: 107.06 beats per minute) was detected in 32 seizures, with ictal onset from the mesial temporal lobe structures in 23/32; 16/32 occurred during the first 10 seconds and 16/32 during the next 20 seconds from the seizure onset independently of the site of origin. Among the different semiological components for each seizure, only dystonic posturing and automatism correlated with HR increments. We did not find bradycardia in our series. 我们记录了100次发作。三次非单次发作从分析中被排除。63/97（65%）有左侧半球区起始发作，主要来自颞叶（57.7%）。平均基线心率是每分钟77次，观察到32次发作中有发作性心动过速（HR：107.06次/分），这32次发作中有23次发作开始来源于颞叶内侧结构，这32次发作中有16次发生在起源区独立癫痫发作开始第一个10秒，剩余16次发生在接下来20秒。在每次发作的不同症状学表现中，仅仅姿势性肌张力障碍和自动症与心率增量相关。在我们的研究中我们没有发现心动过缓。 Ictal tachycardia occurs most frequently with