复方果糖电解质注射液在肾移植后多尿期补液中的临床应用的研究.pdfVIP

Med J Chin PLA, Vol. 39, No. 5, May 1, 2014 　411 论　著 复方果糖电解质注射液在肾移植后多尿期补液中的临床应 用研究 张雷，曾力，韩澍，周梅生，赵闻雨，隋明星，朱有华 [摘要]　目的　观察复方果糖电解质注射液在肾移植术后多尿期的补液效果。方法　回顾性分析2004 年1月－ 20 13年12月上海长征医院1279例肾移植后多尿期的补液治疗方案，均采用复方果糖电解质注射液补液，监测患者的 血电解质、血糖、尿糖、二氧化碳结合力(CO2 CP)及肾功能变化情况。结果　肾移植后多尿期尿量峰值出现在术后 3 ～9h ，其中最高尿量达到2500ml/h 。血钠、钾、氯均在正常范围，血钙处于正常范围的下限，CO2 CP在正常范围， 血肌酐浓度随时间推移而明显下降。术前患者血糖均控制在正常范围内，术后血糖水平略有上升，但多处于正常范围 上限或者稍高于正常值，且术后1周内未出现血糖的剧烈波动。尿糖受手术的影响更小，术后无升高趋势。结论　复 方果糖电解质注射液可较好地维持肾移植后多尿期的水、电解质和酸碱平衡，并能有效解决传统循环补液治疗存在的 液体种类多、操作繁琐和高血糖等问题。 [关键词]　肾移植；补液疗法；果糖；水电解质平衡 [中图分类号]　R6 17　　　　[文献标志码]　A　　　　[文章编号]　0577-7402 (20 14)05-04 11-05 [D OI]　10.11855/j.issn.0577-7402.20 14.05.17 Clinical use of compound fructose electrolyte solution in diuresis stage after kidney transplantation * ZHANG Lei, ZENG Li, HAN Shu, ZHOU Mei-sheng, ZHAO Wen-yu, SUI Ming-xing, ZHU You-hua Organ Transplantation Institute of PLA, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China * Corresponding author, E-mail: zhuyouhua@126.com This work was supported by the Shanghai Committee of Science and Technology Fund (054119633), and the National Health Institute Fund (201002004) [Ab stracts]　Objectiv e　To evaluate the effect of compound fructose electrolyte solution in the diuresis stage after kidney transplantation. Methods　The rehydration therapy was retrospectively analyzed in 1279 cases of diuresis stage after renal transplantation in Changzheng Hospital from J an. 2004 to Dec. 2013. All the patients received compound fructose electrolyte solution intravenously, and the changes in blood electrolytes, blood glucose, urine glucose, CO combining power (CO CP), and renal function were monitored and