复方木尼孜其颗粒联合盐酸西替利嗪片治疗湿疹的可行性研究.docVIP

复方木尼孜其颗粒联合盐酸西替利嗪片治疗湿疹的可行性研究 　　[摘要] 目的 探讨复方木尼孜其颗粒联合盐酸西替利嗪片治疗湿疹的临床疗效和可行性。 方法 整群选取2012年10月―2014年11月该院收治的164例湿疹患者作为研究对象，采用随机数字表法将所选患者分为研究组和对照组，各82例。对照组患者口服盐酸西替利嗪片治疗，剂量：10 mg/次，1次/d；研究组在对照组基础上加用复方木尼孜其颗粒，剂量：：6 g/次，3次/d，两组患者均治疗4周。综合比较两组患者治疗总有效率、不良反应发生率的差异。 结果 研究组患者治疗总有效率为97.6%，高于对照组的86.6%（P0.05）。结论 复方木尼孜其颗粒联合盐酸西替利嗪片治疗湿疹疗效显著，不良反少，安全可行，值得临床推广使用。 　　[关键词] 复方木尼孜其颗粒；盐酸西替利嗪；湿疹 　　[中图分类号] R83 [文献标识码] A [文章编号] 1674-0742（2015）06（a）-0095-02 　　Feasibility Research of Compound Munizi Particles Combined with Cetirizine Hydrochloride Tablets for Eczema Patients 　　ZHAO Shi-yi 　　Department of Dermatology， The Third Affiliated Hospital of Henan University of Traditional Chinese Medicine， Zhengzhou，Henan Province， 450003 China 　　[Abstract] Objective To investigate the effects and safety of compound munizi particles combined with cetirizine hydrochloride tablets treatment for eczema patients. Methods 164 cases of eczema patients in our hospital from 2012 October to 2014 Novemberwere randomly divided into research group and control group，each were 82 cases. Control group were treated with cetirizine hydrochloride tablets for four weeks， with 10mg each time， 4 times a day. Research group were treated with compound munizi particles combined with cetirizine hydrochloride tablets treatment for four weeks， with 6 g each time， 3 times a day.The total effective rate and adverse reactions rate were compared. Results The total effective rate of research group was 97.6%，which washigher than 86.6% of control group （P0.05）. Conclusion Compound munizi particles combined with cetirizine hydrochloride tablets for the treatment of eczema has significant effect. It has few adverse reactions and worthy of clinical widely used. 　　[Key words] Compound munizi particles； Cetirizine hydrochloride； Eczema 　　湿疹是由多种内外因素引起的瘙痒剧烈的一种皮肤炎症反应，以病程长、易复发为特点，对患者的生活质量造成严重影响[1-2]。该研究选取该院于2012年10月―2014年11月收治的164例湿疹患者作为研究对象，旨在探讨复方木尼孜其颗粒联合盐酸西替利嗪片治疗湿疹的临床疗效和可行性，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　整群选取2012年10月―2014年11月该院收治的164例湿