细菌溶解产物治疗老年支气管哮喘合并反复呼吸道感染的临床效果.docVIP

细菌溶解产物治疗老年支气管哮喘合并反复呼吸道感染的临床效果 　　[摘要] 目的 探讨细菌溶解产物治疗老年支气管哮喘合并反复呼吸道感染的临床效果。 方法 选择2011年8月～2014年12月在我院就诊的支气管哮喘合并反复呼吸道感染老年患者90例，根据入院顺序分为治疗组和对照组，各45例。对照组给予常规药物治疗，治疗组在此基础上加用细菌溶解产物治疗。 结果 治疗后，治疗组有效率为97.8%，对照组为86.7%，治疗组有效率明显高于对照组（P0.05）；治疗后，两组的CD4+CD25+ T和CD4+OX40+ T值均明显降低，治疗组的CD4+CD25+ T和CD4+OX40+ T值明显低于对照组（P0.05）。 结论 细菌溶解产物治疗老年支气管哮喘合并反复呼吸道感染，能有效改善机体免疫状况，提高临床治疗效果。 　　[关键词] 老年人；支气管哮喘；呼吸道感染；细菌溶解产物；免疫 　　[中图分类号] R974 [文献标识码] A [文章编号] 1674-4721（2015）08（b）-0121-03 　　Clinical effect of bacterial lysates in the treatment of elderly patients with bronchial asthma with repeated respiratory infection 　　LIU Ming-yan 　　Department of Respiratory Medicine，Mining Group General Hospital of Liaoyuan in Jilin Province，Liaoyuan 136200，China 　　[Abstract] Objective To explore the clinical effect of bacterial lysates in the treatment of elderly patients with bronchial asthma with repeated respiratory infection. Methods 90 elderly patients with bronchial asthma with repeated respiratory infection from August 2011 to December 2014 in our hospital were selected.Patients were divided into control group（n=45） and treatment group（n=45） according to their order of hospitalization.The patients of control group were given routine therapy，and patients of treatment group were given further therapy of bacterial lysates. Results After treatment，the total efficacy was 97.8% in treatment group，significantly higher than 86.7% in control group（P0.05）.After treatment，both CD4+CD25+ T and CD4+OX40+ T between two groups was decreased respectively，and CD4+CD25+ T and CD4+OX40+ T in treatment group was more lower than that of control group（P0.05）. Conclusion Bacterial lysates can effective improve body′s immune status of elderly patients with bronchial asthma with repeated respiratory infection，and promotes the improvement of the clinical curative effect. 　　[Key words] Elderly；Bronchial asthma；Respiratory infection；Bacterial lysates；Immune 　　支气管哮喘是临床上的常见疾病，不仅影响患者的生活质量，而且给家庭和社会带来沉重的经济负担。较多支气管哮喘患者会并发各种疾病，且多发于老