经三腔胃肠管肠内应用波利特于内镜止血术后患者的疗效.docVIP

经三腔胃肠管肠内应用波利特于内镜止血术后患者的疗效 　　【摘要】 目的：探讨患者经三腔胃肠管肠内应用雷贝拉唑（波利特）内镜下止血术后的疗效。方法：采用前瞻性对照研究，对82例急性非静脉曲张性上消化道出血行内镜下止血术，其中试验组45例患者采用留置三腔胃肠管及肠内应用波利特，对照组37例患者采用留置传统胃管及静脉应用奥美拉唑针剂，比较两组胃液pH值、再出血率及并发症的发生率。结果：两组的胃液pH值、再出血率及穿孔发生率比较差异均无统计学意义（P0.05），试验组的并发症程度较轻，并可减少静脉输液量及稳定血糖。结论：经三腔胃肠管肠内应用波利特于内镜止血术后患者效果理想，特别适合应用于合并心功能不全及糖尿病患者。 　　【关键词】 上消化道出血； 雷贝拉唑； 胃肠管 　　【Abstract】 Objective：To explore the effect of pantients upper gastrointestinal hemorrhage after endoscopic operation by intestinal administration of Rabeprazole（Pariet） through triple lumen feeding tube.Method：82 patients with actue nonvariceal upper gastrointestinal bleeding were treated hemostasis under endoscopy and were involved in this prospective random control test.The experimental group of 45 patients were treated with indwelling three cavity gastric tube and intestinal Pollitt applications，and the control group of 37 cases were treated with indwelling traditional stomach tube and intravenous omeprazole injection，the gastric pH，rebleeding rate and the complications rate of two groups were compared and observed.Result：The differences of gastric pH，rebleeding rate and incidence of upper gastrointestinal tract perforation of the two groups were no statistically significant（P0.05）.The experimental group had lesser degree of complications，it could decrease the amount of intravenous fluids and stable blood sugar.Conclusion：The effect of the patients with upper gastrointestinal hemorrhage after endoscopic operation by intestinal administration of Rabeprazole（Pariet） through triple lumen feeding tube is satisfactory.It is especially suitable for application in patients with cardiac insufficiency and diabetes. 　　【Key words】 Upper gastrointestinal hemorrhage； Rabeprazole； Feeding tube 　　急性非静脉曲张性上消化道出血是临床常见急症，随着内镜技术的发展，内镜下止血治疗明显改善了该病的预后。但是，内镜下止血治疗是一种有风险性的治疗手段，可能会引起穿孔等并发症的出现，而且内镜止血治疗也有15%～25%的患者发生再次出血，再次出血则治疗比较棘手[1]。因此，对已行内镜下止血术后患者行后续的巩固治疗及观察也非常重要。本院自2005年2月-2014年6月，对45例行内镜下止血治疗术后患者安置三腔胃肠管（多功能胃肠管），并经三腔胃肠管肠内应用雷贝拉唑（波利特）进行进一步的治疗及观察，效果