放疗联合体外高频热疗治疗中晚期恶性肿瘤的效果观察.docVIP

放疗联合体外高频热疗治疗中晚期恶性肿瘤的效果观察 　　[摘要] 目的 研究放疗联合体外高频热疗治疗中晚期恶性肿瘤的效果。 方法 将2012年4月～2014年3月本院肿瘤科住院治疗的100例中晚期恶性肿瘤患者分为两组，放疗+热疗联合组（治疗组）50例采用CT定位适形放疗，肿瘤放疗剂量45～70 Gy，同期体外高频热疗，设定温度41～43℃，热疗时间40～60 min/次，患者在放疗后60 min进入热疗室，每周配合放疗进行2次热疗，2次间隔3 d，不同肿瘤按放疗剂量不同给予8～14次热疗。单纯放疗组（对照组）50例给予单纯放疗，其放疗方法及剂量同治疗组。治疗过程中详细记录治疗相关毒副反应及肿瘤退缩情况；治疗结束后评估两组患者的肿瘤病灶变化情况、各种治疗相关毒副反应的发生率及生活质量的改善情况。 结果 治疗组患者的总有效率为78.0%，对照组为58.0%，两组差异有统计学意义（P0.05）。治疗结束后治疗组患者的生活质量评分高于对照组（P0.05）。 结论 放疗联合体外高频热疗治疗恶性肿瘤的近期疗效优于单纯放疗，且患者的生活质量改善情况较单纯放疗组好，治疗相关毒副反应的发生率及严重程度与单纯放疗相当。 　　[关键词] 热疗；放疗；恶性肿瘤 　　[中图分类号] R73 [文献标识码] A [文章编号] 1674-4721（2014）09（c）-0053-04 　　Effect observation on radiotherapy combined high-frequency heat treatment of middle-late malignant tumor in vitro 　　LIU Xiao-hong WAN Lin-lin▲ ZHOU Zhen-yuan SONG Wei-ping ZHOU Wen-xing 　　Department of Oncology，People′s Hospital of Xinyu City in Jiangxi Province，Xinyu 338000，China 　　[Abstract] Objective To study the effect of radiotherapy combined high-frequency heat treatment of middle-late malignant tumor in vitro. Methods 100 patients with middle-late malignant tumor hospitalized in Department of Oncology in our hospital from April 2012 to March 2014 were divided into two groups，radiotherapy+heat joint group （treatment group） in 50 cases were given CT positioning conformal radiation therapy，the extent of radiation dose of 45 to 70 Gy，extracorporeal high-frequency heat during this period，the set temperature was 43 to 41 ℃， 40 to 60 min/time，heat treatment time in patients with 60 min after radiation into heat chamber，thermal therapy，cooperate with radiation therapy in 2 times a week 2 times interval of 3 d，different tumor according to the radiation dose for 8 to 14 times thermal therapy.Simple radiotherapy group （control group） in 50 cases were only given radiation therapy，the same method and dose radiotherapy with treatment group.The treatment-related toxicity and tumor regression were detailed recorded in the process of the treatment，The tumor lesion changes，all kinds of tre