教育文件生物化学chap8TCAHMP.pptVIP

TCA …… Tricarboxylic acid cycle Citric acid cycle Definition The cycle oxidizes pyruvate to CO2 and H2O , with the concomitant production of energy (ATP). Location The cycle occurs within the mitochondria（线粒体） of eukaryotes（真核生物） and cytosol（细胞质） of prokaryotes （原核生物）. Section 1 The cycle process TCA How many ATP molecules are generated with 1 molecule of pyruvate through TCA pathway? How many ATP molecules are generated with 1 molecule of glucose through EMP-TCA pathway?( one glucose is oxidized to CO2 and H2O.) EMP :8 Pyruvate to acetylCoA:6 TCA cycle:24 Physiological importance