清热除湿法治疗急性痛风性关节炎（湿热蕴结证）临床观察.docVIP

清热除湿法治疗急性痛风性关节炎（湿热蕴结证）临床观察 　　【摘 要】目的：观察清热除湿内外合治的方法治疗急性痛风性关节炎（湿热蕴结证）的临床疗效。方法：将60例急性痛风性关节炎（湿热蕴结证）患者随机分为治疗组和对照组，每组30例。对照组采用秋水仙碱治疗；治疗组采用竹叶石膏汤加减口服配合痛风清洗剂外洗治疗。两组疗程均为5 d。观察两组临床疗效及治疗前后血尿酸、红细胞沉降率、C-反应蛋白的变化情况。结果：治疗组显效16例，有效12例，无效2例，总有效率为93.33%；对照组显效14例，有效13例，无效3例，总有效率为90.00%。两组比较，差异无统计学意义（P 0.05）。治疗后，两组红细胞沉降率、C-反应蛋白均明显降低（P 0.05）；治疗组血尿酸明显降低（P 0.05），两组比较，差异有统计学意义（P 0.05）。对照组不良反应发生率高于治疗组（P 0.05）。结论：清热除湿法内外合治急性痛风性关节炎（湿热蕴结证）有良好疗效，且无明显不良反应。 　　【关键词】 急性痛风性关节炎；湿热蕴结证；清热除湿法；内外合治 　　doi：10.3969/j.issn.2095-4174.2015.10.004 　　【ABSTRACT】 Objective：To observe the clinical effect of clearing heat and removing dampness in the treatment of acute gouty arthritis.Methods：60 cases of acute gouty arthritis were randomly divided into a treatment group and a control group，30 cases in each.The control group was treated with colchicine；while the treatment group with modified Zhuye Shigao Tang （竹叶石膏汤） combined with cleaning agent for gout.They were treated for 5 days.The clinical efficacy and the changes of blood uric acid，erythrocyte sedimentation rate，and C- reactive protein of the two groups were compared.Results：In the treatment group，16 cases were markedly effective，12 cases were effective，and 2 cases were ineffective，the total effective rate being 93.33%；while in the control group，14 cases were markedly effective，13 cases were effective，and 3 cases were invalid，the total effective rate being 90%.There was no significant difference between the two groups （P 0.05）.After treatment，the erythrocyte sedimentation rate and C- reactive protein in the two groups significantly decreased （P 0.05）；the blood uric acid was significantly lower in the treatment group （P 0.05），difference between them being statistically significant （P 0.05）.The incidence of adverse reactions in the control group was higher than that in the treatment group （P 0.05）.Conclusion：Method of clearing heat and removing dampness has a good curative effect to treat acute gouty arthritis，safety and with no obvious adverse r