阿托伐他汀联合丹红注射液治疗不稳定型心绞痛疗效观察.docVIP

阿托伐他汀联合丹红注射液治疗不稳定型心绞痛疗效观察 　　doi：10.3969/j.issn.1007-614x.2014.12.58 　　摘 要 目的：探讨阿托伐他汀联合丹红注射液治疗不稳定型心绞痛的临床疗效。方法：2013年2月-2014年2月收治不稳定型心绞痛患者80例，随机分成观察组和对照组，各40例。对照组给予血管紧张素转换酶抑制剂、钙离子拮抗剂、β受体阻滞剂、硝酸酯类，抗血小板聚集及阿司匹林进行治疗；观察组给予口服阿托伐他汀40mg/日，静滴0.9%氯化钠注射液250ml+丹红注射液40ml/日，两组均连续治疗14天。结果：观察组显效18例（45.0%），有效19例（47.5%），无效3例，总有效率92.5%；对照组显效7例（17.5%），有效21例（52.5%），无效12例，总有效率70.0%。两组比较差异有统计学意义（P0.05）。结论：阿托伐他汀联合丹红注射液治疗不稳定型心绞痛临床疗效显著，值得推广。 　　关键词 不稳定型心绞痛（UAP） 阿托伐他汀 丹红注射液 　　Efficacy observation of atorvastatin combined with Danhong injection in the treatment of unstable angina 　　Zhang Guangming 　　The Traditional Chinese Medicine Hospital of Bo’ai County，Henan 454450 　　Abstract Objective：To evaluate clinical efficacy of atorvastatin combined with Danhong injection in the treatment of unstable angina.Methods：80 patients with unstable angina were selected from February 2013 to February 2014.They were randomly divided into the observation group and the control group with 40 cases in each.The control group was given angiotensin converting enzyme inhibitors，calcium antagonists，β receptor blockers，nitrates，anti-platelet aggregation and aspirin therapy.The observation group was given oral atorvastatin 40mg/day，intravenous 0.9% saline 250ml and Danhong injection 40ml/day.The both groups were continuously treated for 14 days.Results： In the observation group，18 cases（45.0%） were markedly effective，19 cases （47.5%） were effective，3 cases were invalid.The total efficiency was 92.5%.In the control group，7 cases（17.5%） were markedly effective，21 cases（52.5%） were effective，12 cases were invalid.The total efficiency was 70.0%.The two groups were significantly different（P0.05）.Conclusions：The clinical effect of atorvastatin combined with Danhong injection in the treatment of unstable angina is significant，and it is worthy of promoting. 　　Key words Unstable angina pectoris（UAP）；Atorvastatin；Danhong injection 　　不稳定型心绞痛（UAP）是心内科的常见病之一[1]，多发于老年人，由于病情较重，若不及时正规治疗，很容易导致猝死。阿托伐他汀具有调脂、降脂、保护心血管的作用。丹红注射液主要成分是丹