甲状腺功能减退症的临床治疗效果观察.docVIP

甲状腺功能减退症的临床治疗效果观察 　　[摘要] 目的 探讨甲状腺功能减退症的临床治疗研究进展。 方法 选择2009年8月～2012年8月来本院就诊的83例原发性甲状腺功能减退症患者，根据年龄、病情程度和个体差异分为A组和B组，A组给予左旋甲状腺素片部分替代治疗，B组给予激素完全替代治疗，选择40例患者联合中药治疗，其中A组14例，B组26例。通过观察患者治疗前后血清T3、T4和TSH的变化来评估分析不同方案治疗的总体疗效。 结果 A、B组中合并中药组的总有效率明显高于非合并中药组，差异有统计学意义（P0.05）；A、B组治疗后FT3、FT4均明显升高，TSH治疗后明显降低，差异有统计学意义（P0.01）。 结论 说明中成药的联合应用能良好改善患者的临床症状、体征，良好改善患者的病情和生活质量；两组不同激素替代治疗方案明显改善了患者血清FT3、FT4和TSH值，使其达到较为适宜范围，良好改善了患者的病情。 　　[关键词] 甲状腺功能减退症；临床表现；激素替代；治疗研究 　　[中图分类号] R581.2 [文献标识码] A [文章编号] 1674-4721（2013）11（a）-0032-02 　　The clinical effect observation of hypothyroidism 　　ZHANG Jin 　　Outpatient Department of Logistics Department，Hebei Province Public Security Fire Department，Shijiazhuang 050035，China 　　[Abstract] Objective To investigate the research progress of clinical treatment of hypothyroidism. Methods 83 primary hypothyroidism patients during 2009 August to 2012 August in our hospital were selected.The patients were divided into group A and group B，according to age，severity of disease and individual differences，group A was given euthyrox treated and group B was given hormone treated.40 patients contained 14 patients of A group and 26 patients of B group were selected to receive traditional Chinese medicine.The overall curative effects of different therapy methods were assess by observed the changes of serum T3，T4 and TSH. Results The total efficiency of group combined with traditional Chinese medicine was markedly higher than the group uncombined of traditional Chinese medicine group（P0.05）；The FT3 and FT4 of group A and group B were significantly increased，TSH decreased significantly after treatment （P0.01）. Conclusion The combination of Chinese medicine can improve patient′s clinical symptoms and the life quality；Two groups of different hormone replacement therapy can mediate the FT3，FT4 and TSH to suitable range，which improve the patient′s condition. 　　[Key words] Hypothyroidism；Clinical manifestation；Hormone replacement therapy；Treatment research 　　近年来，甲状腺功能减退症的发病