点阵激光联合景天祛斑胶囊治疗女性黄褐斑短期临床观察.docVIP

点阵激光联合景天祛斑胶囊治疗女性黄褐斑短期临床观察 　　[摘要]目的：观察点阵激光联合景天祛斑胶囊治疗女性黄褐斑的短期疗效和安全性。方法：将75例女性黄褐斑患者随机分为治疗组、对照1组和对照2组，每组各25例。三组患者均服用VitC和VitE，对照1组和对照2组外用熊果苷凝胶。治疗组同时予点阵激光治疗联合景天祛斑胶囊口服，对照1组同时予景天祛斑胶囊口服治疗。点阵激光治疗每4周1次，共3次；景天祛斑胶囊口服4粒，2次/天，疗程12周。结果：治疗组有效率为84.0%，对照1组为64.0%，对照2组为36.0%，三组差异有显著性（均P＜0.05）；三组患者满意度比较差异亦有显著性（均P＜0.05），与医师疗效评价基本一致；治疗组激光术后均出现短期的红斑、水肿和灼热，疗程结束后随访均未见色素沉着；对照1组和对照2组未出现明显不良反应。结论：点阵激光联合景天祛斑胶囊治疗黄褐斑短期疗效好，安全性高，不良反应轻，可作为治疗黄褐斑的一种选择。 　　[关键词]黄褐斑；点阵激光；景天祛斑胶囊；女性 　　[中图分类号]R758.4+2 [文献标识码]A[文章编号]1008-6455（2014）08-0669-03 　　 　　Short-term clinical observation of fractional laser combined with JingTianQuBanJiaoNang for the treatment of females melasma 　　ZHANG Guo-ping,HUANG Zhuang-feng,DONG Jia-hui,HUANG Xiao-xiong 　　（Huizhou Dermatology Hospital,Huizhou 516001,Guangdong, China） 　　 　　Abstract: Objective To observe the safety and the short-term efficacy for treating females melasma by Fractional laser combining with JingTianQuBanJiaoNang.Methods75 cases of females melasmapatients were randomly divided into treatment group and control 1 and control 2 groups, 25 cases in each group. All patients were taking VitC and VitE. The control 1 and control 2 use topical arbutin gel. The treatment group were treated once every 4 weeks for 3 times by Fractional laser combining with taking JingTianQuBanJiaoNang 4 capsules one time and 2 times a day for 12 weeks.The control 1 were taking to JingTianQuBanJiaoNang. ResultsThe markedly effective rate of the treatment group was 84.0% and that of the control l and 2 was 64.0% and 36.0% respectively.There were significant differences among three-groups effective rate (P＜0.05).The patient satisfaction among three groups showed significant differences too(P＜0.05),consisting with the physicians efficacy evaluation. Patients receiving laser therapy, all suffered short-term erythema, edema and calorescence at the treatment site after each laser therapy, but no pigmentation.The control 1 and 2 didnt occur significantly adverse reaction.Conclusion Fractiona