盐酸帕罗西汀联合心理干预对慢性心力衰竭合并焦虑抑郁障碍患者的临床观察.docVIP

盐酸帕罗西汀联合心理干预对慢性心力衰竭合并焦虑抑郁障碍患者的临床观察 　　doi：10.3969/j.issn.1007-614x.2014.15.16 　　摘 要 目的：对盐酸帕罗西汀联合心理干预对慢性心力衰竭合并焦虑抑郁障碍患者的临床疗效进行观察。方法：收治慢性心力衰竭合并焦虑抑郁障碍患者60例，随机分成对照组和观察组，各30例。对照组采取常规治疗，观察组采取盐酸帕罗西汀联合心理干预治疗。结果：治疗后，在CO、LVEF以及FS方面，对照组明显低于观察组（P0.05）；在SDS以及SAS评分方面，观察组明显低于对照组（P0.05）。结论：慢性心力衰竭合并焦虑抑郁障碍患者采取盐酸帕罗西汀联合心理干预治疗方式，能使患者焦虑抑郁症状得到有效的改善，有助于临床疗效以及生活质量的提升。 　　关键词 盐酸帕罗西汀 心理干预 慢性心力衰竭 焦虑抑郁 　　Clinical observation of paroxetine hydrochloride combined with psychological intervention on patients with chronic heart failure combined with anxiety and depression 　　Jin Xiuzhi，Sun Xueli，Guo Xiaoli，Ning Bin 　　Internal Medicine-Cardiovascular Department，the Peoples Hospital of Fuyang City，Anhui 236000 　　Abstract Objective：To explore the clinical curative effect of paroxetine hydrochloride combined with psychological intervention on patients with chronic heart failure combined with anxiety and depression.Methods：60 patients with chronic heart failure combined with anxiety and depression were selected.They were randomly divided into the observation group and the control group with 30 cases in each.The control group was treated with conventional therapy，and the observation group was treated with paroxetine hydrochloride combined with psychological intervention.Results：After treatment，in the CO，LVEF and FS，the control group was significantly lower than those in the observation group（P0.05）.In the SDS and SAS score，the observation group was significantly lower than that of the control group（P0.05）.Conclusion：The application of paroxetine hydrochloride combined with psychological intervention in the treatment of patients with chronic heart failure combined with anxiety and depression can significantly improve the symptoms of anxiety and depression and the clinical efficacy and quality of life. 　　Key words Paroxetine hydrochloride；Psychological intervention；Chronic heart failure；Anxiety and depression 　　在临床中，心脏病的严重阶段就是慢性心力衰竭，具有较高的病死率以及致残率[1]。相关研究表明，慢性心力衰竭患者发生焦虑抑郁的概率比较高，不仅会降低患者的临床疗效以及生活质量，同时