MRICorrectionSoftware-r2labs.org.pptVIP

Software Development For Correction of Gradient-Nonlinearity Distortions in MR Images T.S. Lee, K.E. Schubert Computer Science CSUSB Functional Proton Radiosurgery Functional Neurosurgery Trigeminal Neuralgia Parkinson’s Disease Brain regions ( 1 cm) Proton Radiosurgery Accurate to less than 1 mm MRI for target localization Distinguish tissue types 512?512 images 262,144 pixels/study Gradient nonlinearity distortions (~2mm) Example MR Phantom Images Bad Slides Finding Edges Disconnects Remove Extraneous Features Can We Fix it? Example Edge Images Midplanes Ideal Planes Shift ±? the phantom dimension Perpendicular to face Distortion Modeling Magnetic Field of Cylinder Sum of spherical harmonics: Distortion Modeling Applying Distortion CorrectionAxial Plane Applying Distortion CorrectionCoronal Plane Applying Distortion CorrectionSagittal Plane Results Theoretical undistorted points vs. corrected points Standard deviations of correction +X face: Standard Deviation = 0.23503 mm -X face: Standard Deviation = 0.25168 mm +Y face: Standard Deviation = 0.15322 mm -Y face: Standard Deviation = 0.15823 mm +Z face: Standard Deviation = 0.13548 mm -Z face: Standard Deviation = 0.14173 mm Conclusions 3s range 0.4 – 0.8 mm 1-2 pixels on each image Originally 2mm (5-6 pixels) Accurate localization of anatomical targets Future Work Further verification and testing Clinical trials FDA approval Treatment on humans * * R.W. Schulte Radiation Medicine LLUMC Sagittal Plane Coronal Plane Axial Plane Partial Phantom Partial Phantom No Phantom Off Center Phantom Air Bubble Leaky Slice Axial Plane Coronal Plane Sagittal Plane Calculate Midpoints Fit Midplane Ideal shape, size, and orientation of phantom’s faces Stack Midpoints Measured Corrected