吲达帕胺联合氨氯地平治疗高血压合并冠心病的价值.docVIP

吲达帕胺联合氨氯地平治疗高血压合并冠心病的价值 　　[摘要] 目的 观察高血压合并冠心病采用吲达帕胺联合氨氯地平治疗的临床效果。 方法 分析2013年5月～2015年5月本院收治的88例高血压合并冠心病患者的临床资料，将其按照随机数字表法分为实验组与对照组。对照组患者给予硝苯地平控释片进行治疗，实验组患者给予吲达帕胺联合氨氯地平进行治疗。比较两组患者的临床治疗效果。 结果 实验组患者的治疗总有效率为93.2%（41/44），明显高于对照组的72.7%（32/44），两者差异有统计学意义（P0.05）；治疗后两组患者血压均明显改善（P0.05）。 结论 高血压合并冠心病采用吲达帕胺联合氨氯地平治疗的效果显著，值得进一步推广。 　　[关键词] 吲达帕胺；氨氯地平；高血压合并冠心病 　　[中图分类号] R544.1 [文献标识码] A [文章编号] 1674-4721（2016）04（b）-0131-03 　　[Abstract] Objective To observe the clinical effect of Indapamide combined with Amlodipine in treating hypertension complicated with coronary artery disease. Methods Data of 88 hypertension complicated with coronary artery disease patients from May 2013 to May 2015 of our hospital were analyzed.Patients were divided into experimental group and control group according to random number table.Patients in control group were given Nifedipine Controlled Released Tablets，and patients in experimental group were given Indapamide combined with Amlodipine.The clinical treatment effect of two groups was analyzed. Results The total effective rate of experimental group was 93.2% （41/44），which was obvious higher than that was 72.7% （32/44） in control group，and the difference was statistical significant （P0.05）；after treatment，the blood pressure in two groups improved obviously（P0.05）. Conclusion Using Indapamide combined with Amlodipine in treating hypertension complicated with coronary artery disease has obvious effects and is worth to study and popularize. 　　[Key words] Indapamide；Amlodipine；Hypertension complicated with coronary artery disease 　　作为临床上一种常见的心血管疾病，高血压有着较高的发病率[1]。相关调查研究显示，高血压发病率与患者年龄呈正相关[2]。若患者长期处于高血压状态，极易出现心、脑、肾等重要组织器官的并发症，影响患者的生活质量和生命安全，现该病已引起了人们的高度关注[3]。冠心病是高血压常见的并发症之一，高血压合并冠心病在临床上较为常见，多发于中老年人，需通过长期服药的方式来改善预后[4]。本研究以88例高血压合并冠心病患者为研究对象，探讨吲达帕胺联合氨氯地平的治疗效果。 　　1 资料与方法 　　1.1 一般资料 　　收集2013年5月～2015年5月本院收治的88例高血压合并冠心病患者的临床资料，将其按照随机数字表法分为实验组与对照组。实验组44例患者中，男30例，女14例；年龄50～80岁，平均年龄（68.5±8.4）岁；病程3～10年，平均病程（6.3±3.3）年。对照组44例患者中，男31例，女13例；年龄50～80岁，平均年龄（68.8±8.3）岁；病程