乙型肝炎产妇乳汁乙肝病毒标志物检测与哺乳指导.pdfVIP

· 336· Journal。f Nursing Scie rice May 2002 Vol l7 No．5 乙型肝炎产妇乳汁乙肝病毒标志物检测与哺乳指导 许细叶 陈红 刘海意 华中科技大学同济医学院附属同济医院妇产科，武汉 430030 摘要 目的探讨乙型肝点产妇产后能否进行母乳喂养。方法 选择住院分娩的乙型肝置产妇 】s0倒(肝功能均 正常)，其中血清HBsAg阳性70倒为单阳组．HPxsAg厦HBeAg均阳性7l侧为双阳组。分别留取产后3～ d的初 乳进行乳汁乙肝璃毒标．七物(HBV M)辁驯。结果 两组乳汁中HBsAg、IIBeAg、HBcAb、HBV DNA阳性率比较，差 畀有显著性意义(P0 05j 结论 框据HBV—M各项指标阳性的临床价值分析产妇初乳中HBeAg、HBV DNA阳 性厦产妇血清中双阳者(HBsAg、H Ag阳性)不宜哺乳，初乳中单纯HBsAg阳性．而HBVDNA为阴性的产妇可 以哺乳，但应给予正确的哺乳指导。 关键词：肝竞．乙型； 乳汁： 乙肝璃毒标志物： 母乳喂养 中图分类号：Rl74 ．4~R512．6 2 文献标识码：A 文章编号：1001—4132(2002)05—0336—02 Detection of Hepatitis B Virus Marker in the Parturients with Hepatitis B and Lactational Instruction／／Xu X r Chert Hong b Ha r Department of Obstetrics and( necalogy-Tongji Hospita1．TonglMedical College， Huazhong Umver．1ity of Sctence and Technology-~Vuhan 430030 Abstract：Objective To stuty the breast feeding of the parturients with hepatitis B after delivery．Methods 130 parturients with hepatitis B(1iver function was no rma1)were selected and divided into two groups：single positive group( =79)positive for serum HbsAg and double positive group( 一71)positive for both HbsAg and HbeAg． Hepatitis B virus ma rke r(HBV—M)was detected in the co]ostrum 3 to 5 days after dehvery．Results There WaS very significant difference in the po．~itive rate of HbsAg，HbeAg，HbeAg and HBV DNA in the milk between the two groups( 0．05) Conclusion In~eFHIS of the clinlcaI imp[ication of HBV-M ，the parturients with the co[ostrum positive for HbeAg，HBV DNA and those with the serlJm double positive for HbsAg and HbeAg were not suitable for breast feeding The parturlents with the eo[ostrum positive for HbsAg，but negative for HBV DNA were~uitable for beast feeding Key words：hepatiti,s B； milk； hepatitis B virus marker； breast feeding