北京市学龄儿童青少年骨密度正常参考值的研究.pdfVIP

134 垦量亟堕塑盘查 2003匀三5月第9卷第2期 Chin J Osteoporos，May．2003 Vol 9，N0．2 · 论 著 · 北京市学龄儿童青少年骨密度正常参考值 的研究 张李伟 刘加昌 翟凤英 曹若湘 段佳丽 【摘要l 目的 提供北京学龄儿童青少年全身及各部位骨密度的正常参考值，服务于临床及科 研应用。方法 使用双能 x线骨密度仪(DEXA)测量北京市 1025名 6—18岁学龄儿童青少年全身骨 密度(113MD)，以及包括头、胸、中腹、骨盆、下肢及上肢在内躯体各部位骨密度(BMD)，并与国外同类 研究进行比较。结果 骨矿化过程在儿童期为渐进形式，在青春期呈现加速趋势：在躯体各部位及全 身的各个阶段都存在着显著的性别及年龄差异。尽管骨的发育因躯体部位、性别及尺寸大小而异，但 是女性在 10．15岁年龄段倾向于骨密度高于同年龄组男性，而自16岁以后则男性骨密度高于女性(头 部除外)。部份原因是女性骨矿化增长加速过程发动时序早于男性。与白种儿童相比较，这些受试对 象TBMD较低。结论 骨的发育因性别、年龄、部位及种族而呈现不同规律，在评价时应予以考虑。 【关键词】 骨；发育；DEXA；儿童；青少年 Normal reference values for bone mineral density in children and abolescents aged 6一l8 years，B蜘ing， China ZHANG Liwei，L1U J hm喀，ZHA1 Fen鼍啊 ，et越．1n5t讧ule ofNutrition and Food Safety．Chinese Centerfor Disease Control and e ” ，l，Beiji,~ 100050，China 【Abstract】 Objective The paper aims to provide normal values for the assessment of bone status in ehil． dren and adolescents to serve clinical as well as research purposes．Methods Normal values of bone mineral density for total body(TBMD)and selected regions of interest(BMD)，including head，chest，midriff，pelvis， legs and a／lns，were derived from measurements on 1025 children and adolescents 6 to 8 years from Beijing city． BMD was determined by dual—energy x—ray absorptiometry(DEXA)．Results Bone mineralization increased gradually in early childhood and accelerated during adolescence and there were significant age and gender effects on all regions of interest as well as on total body．Although development of bone Was heterogeneous in term of seX． magnitude and localization，it seems females had a higher BMD than their counterparts between the ages of 10 and 15years，from age 16 years，it is quiet on the contrary except BMD for head．Parts ofrol1．sons were due to females ‘ earlier outset of acceleration for increase on BMD．Compared with white—origin chi