北京大学群体遗传学课件.pdfVIP

Population Genetics 种群遗传学 2015-2016 第二学期 每周四 3-4节 三教201 姚蒙 yaom@ Office ：新生物楼312 助教：郑逸韬 ppflying@ 答疑时间：课后或预约 Grading Class participation 20% Mid-term Exam 40% Final Exam 40% What we cover in this course: Concepts and theories Case studies Topics to be discussed ?Mendelian and molecular genetics ?Hardy-Weinberg equilibrium ?Selection ?Genetic drift ?Mutation ?Neutral theory ?Coalescence ?Population subdivision ?Gene flow ?Inbreeding ?Linkage disequilibrium ?Quantitative genetics ?Human population genetics ?Conservation genetics Caution: may not cover them all; not necessarily in this order. Reading materials Matthew Hamilton, Philip Hedrick, Daniel Hartl 2009 4th Edition 2009 Andrew Clark, 4th Edition 2006 What we don’t cover in this course: Microbes, haploids, fungi Software usage, computer skills Too complicated math and algorithm I. Introduction Definition A brief history What is population genetics? ?The theoretical and empirical analysis of genetic variation in populations and the evolutionary processes* responsible for generating and shaping that variation over time. * mutation, selection, genetic drift, gene flow ?Concerned with the origin, amount and distribution of genetic variation present in popula