小细胞肺癌临床特征与治疗疗效相关性研究.docVIP

学科代码03b 小细胞肺癌临床特征与治疗疗效相关性研究 目的：结果：小细胞肺癌；临床征；血清钠；NSE；；PFS；预后 The study on the clinical features of patients with small cell lung cancer and the correlation between therapeutic effect fourth hospital of Hebei medical university,the respiratory department 【ABSTRACT】Objective: This study will start from the clinical features of SCLC patients and so on to investigate the prognostic factors and to provide better the basis for the improvement of survival and prognosis in patients .Methods: The 52 cases of small cell lung cancer patients were collected that were hospitalized in the respiratory department from February 2006 to April 2013. We record the clinical information for all patients.The Mann - Whitney U nonparametric rank and inspection is a first-line treatment in patients with different clinical features of PFS difference, P ?0.05, said the difference was statistically significant.Results：1 In this study, 39 cases of male patients , accounted for 75%, 13 case of female patients, accounted for 25%; ?60 years old in 29 cases, accounted for 55.8%, 23 patients with 60 or older, accounted for 44.2%; 30 cases of smokers accounted for 57.7%, 22 cases of nonsmokers, accounted for 42.3%; 25 patients with limit stage, accounted for 48.1%, 27 patients with extensive stage, accounted for 51.2%.17 cases of patients with serum sodium ?135mmol/l accounted for 44.7%, 21 cases of patients with normal serum sodium, accounted for 55.3%.NSE 16.3ng/ml in 36 cases, accounted for 97.3%, 16.3ng/ml in 1 case, accounted for 0.7%; the average value 95ng/ml. NSE95ng/ml in 28 cases, accounted for 75.7%, 95ng/ml in 9 cases, accounted for 24.3%; after the 2 cycle of chemotherapy return to normal is 15 cases, accounted for 60%, 10 cases of NSE is 16.3ng/ml, accounted for 40%.Three cycles of chemotherapy to radiotherapy is defined as early radiotherapy, a total of 10 cases (58.8%), and chemotherapy cycle after three cycles and 3 radiations is defined as late radiation, a total of 7 cases, acco