ABO hemolytic disease of newborn serum antibody detection and clinical significance of.docVIP

 PAGE \* MERGEFORMAT 7 ABO hemolytic disease of newborn serum antibody detection and clinical significance of [Abstract] Objective analysis and detection of serum antibodies in ABO hemolytic disease of the results, discusses implications for early diagnosis of neonatal ABO hemolytic disease of the extent of the disease. Methods ABO hemolytic disease of the newborn diagnosed 146 cases, according to the results of serum antibody into A Group: direct antiglobulin serum antibody in 79 cases (45.89%), B group: a direct anti-human globulin serum antibodies, the release of antibody and free antibody (hereinafter referred to as the “three antibody” 67 cases (45.89%), compared two groups with jaundice, anemia clinical relationship. Results A group of total bilirubin concentrations were lower than the time B group B group were higher than those of hemoglobin (P lt;0.05 or P lt;0.01). Conclusions The serum antibody detection for early diagnosis and evaluation of disease extent has clinical significance. [Keywords:] Jaundice, newborn, hemolysis, blood group incompatibility, antibody ABO hemolytic disease of newborn early neonatal hyperbilirubinemia (the common cause of hyperbilirubinemia. Serum antibody detection is the main basis for diagnosis of the disease. To understand the extent of early diagnosis and whether the close relationship with the disease, By the author of 146 cases of ABO hemolytic disease of the newborn immune serum anti-human globulin antibodies directly, the release of antibody, free antibody (hereinafter referred to as the “three antibodies”) test results with jaundice, anemia levels were analyzed retrospectively to investigate the impact on the Early diagnosis and clinical symptoms of disease to determine the degree of clinical significance. 1 Materials and Methods 1.1 General information on 146 cases of this group, 87 patients were male, female 59, male to female ratio is 1.47:1, both pediatric hospital in February 2005 ~ February 2007