Albumin in the history and progress in the treatment of cirrhosis of the liver.docVIP

 PAGE \* MERGEFORMAT 17 Albumin in the history and progress in the treatment of cirrhosis of the liver [Abstract] In view of the majority of clinicians to the existence of errors applied to albumin, this article focuses on the clinical application of talk from the albumin, Recalling its tortuous process of historical development of the ignorant and the half century of clinical application, combined with its application in the treatment of cirrhosis of the liver progress, is intended to elaborate the clinical indications, effect, and through its development history, current clinical application, the application of its future prospects. this appeal to clinicians, the correct application of albumin to albumin can be expected make greater contributions to mankind. [Keywords:] albumin, cirrhosis of the liver Albumin, also known as albumin, is a medium molecular weight colloid, spherical, soluble in water. Serum albumin is the most abundant serum protein, plasma total protein accounted for 50% to 60%, half-life cycle 18 to 20 days. The liver is the major human plasma albumin synthesis sites. 1 albumin Features 1.1 The primary role of albumin permeability of the formation of plasma colloid osmotic pressure accounts for 80% of major regulator of vascular tissue and the dynamic balance between the water. As high molecular weight of albumin, compared with the salts and water through the membrane velocity slower, so that albumin colloid osmotic pressure to compete with the capillary static pile, in order to maintain normal blood volume with a constant, while in the circulation, 1g albumin may retain 18mL of water, 5g of each cycle to retain water in the albumin capacity equivalent to about 100mL 200mL of whole blood plasma or the function of which played to increase circulating blood volume and maintain the role of plasma colloid osmotic pressure, albumin can also be combined cation anion, can transport different substances, toxic substances can also be tra