Atorvastatin in elderly patients with coronary heart function and endothelium-dependent vasodilation of pulse wave velocity.docVIP

 PAGE \* MERGEFORMAT 12 Atorvastatin in elderly patients with coronary heart function and endothelium-dependent vasodilation of pulse wave velocity Of: Duxiao Zhi Li Li Wang XR Wang Yuanyuan Jiang Guihua [Abstract] Objective To explore coronary heart disease patients taking atorvastatin 1 year brachial artery endothelial dependent vasodilatation (FMD) and pulse wave velocity (PWV). Methods 35 patients selected (gt; = 60 years) long-term use atropine atorvastatin in patients with coronary heart disease as the atorvastatin group, selected 25 patients (gt; = 60 years) never used lipid lowering drugs in patients with coronary heart disease as those not taking atorvastatin group, 20 patients (“60 years old) people as healthy control group, atorvastatin group on the basis of conventional therapy, taking atorvastatin 10 mg, 1 times / d, orally at bedtime, treatment for 1 year. using high frequency ultrasound before and after treatment and Colin VP 1000 Check the FMD and PWV, also measured blood lipids. Results atorvastatin group before and after treatment did not take atorvastatin group FMD (P lt;0.05), PWV (P lt;0.05) and lipid (P lt;0.05) significantly improved. Conclusions patients with coronary heart disease atorvastatin not only lipid but also to improve FMD and PWV, thereby improving arterial elasticity. [Keywords:] Coronary heart disease; atherosclerosis; atorvastatin; endothelium-dependent vasodilation; pulse wave velocity [Abstract] Objective To investigate the effect of atorvastatin on flow mediated brachial artery vasoactivity (FMD) and pulse wave velocity (PWV) in patients with coronary artery disease. Methods 35 patients (gt; = 60 years old) with coronary artery disease long term using atorvastatin were selected into atorvastatin group, and 25 patients (gt; = 60 years old) with coronary artery disease never using lipid regulating drugs were selected into non atorvastatin group. 20 healthy yonger people (lt;60 years old) were selected into cont