Effect of glutamine on nutrition in patients with chronic obstructive pulmonary disease and antioxidant therapy immunomodulatory role.docVIP

 PAGE \* MERGEFORMAT 11 Effect of glutamine on nutrition in patients with chronic obstructive pulmonary disease and antioxidant therapy immunomodulatory role Of: Yan Li Chun-Xia Liu Chao Ping WEI Xin Zia [Abstract] Objective To study glutamine in chronic obstructive pulmonary disease (COPD) patients with acute exacerbation of nutritional status, immune function and antioxidant effects. Methods 115 patients with acute exacerbation of COPD were randomly assigned to conventional treatment group and the Valley ammonia amide group (Gln) groups. conventional treatment group received conventional nutrition therapy, Gln group, oral glutamine 10 g, 3 times a day, continuous treatment with 10 d. Results Gln group triceps skinfold thickness , long upper arm muscle circumference and plasma total protein and other nutritional parameters improved significantly compared with the conventional group. Gln group IgG, IgA, CD3, CD4, CD4/CD8 and glutathione (GSH) was significantly higher (P lt;0.05). Conclusion Glutamine can improve patients with acute exacerbation of COPD nutrition and immune function, but also can improve the antioxidant capacity. [Keywords:] Chronic obstructive pulmonary disease; glutamine; nutrition; immunization; antioxidant Chronic obstructive pulmonary disease (COPD) has a high morbidity and mortality, serious harm to health of the elderly. COPD with acute exacerbation of elderly patients with severe immune dysfunction and malnutrition (1), so to improve their immune function and nutrition treatment to improve the prognosis is extremely important. In this study, application of glutamine (Gln) of COPD patients with acute exacerbation of treatment, not only to observe its effect on COPD patients with acute exacerbation of immune function, nutritional status, and the observation of treatment changes before and after the antioxidant index. 1 Subjects and methods 1.1 Clinical Data Selection February 2006 to October 2008 in Hebei Province, 115 ca