Elderly patients with controlled analgesia with sufentanil dose of intravenous.docVIP

 PAGE \* MERGEFORMAT 10 Elderly patients with controlled analgesia with sufentanil dose of intravenous Of: Zhangning Ping, Liu, Zhi-Qiang Pan, Zhang Min [Abstract] sufentanil in elderly patients with a reasonable dose of postoperative analgesia, clinical efficacy and safety. Methods 60 patients undergoing elective laparoscopic cholecystectomy under general anesthesia in elderly surgical patients were randomly divided into three groups, each of 20 cases , were used after the background amount of 1g / h (A group), 1.5g / h (B group), 2g / h (C group), intravenous sufentanil analgesia. observed after 4,8, 16,24,48 h for visual analog (VAS) pain score, Sedation sedation scores, vital signs, adverse reactions and analgesia infusion pumps. Results changes in vital signs among the three groups, no significant difference in adverse reactions, A group rest after 8h, 12h, 24h and coughing VAS scores were higher than the B, C group (P lt;0.05). C group Sedation scores were significantly higher than that of A, B group (P lt;0.05). A group of PCA analgesia pump Press the number of actual, effective press times were significantly higher than that of B, C group (P lt;0.05). the total amount of sufentanil 48h A, B group was no significant difference (Pgt; 0.05), C was significantly increased (P lt;0.05 ). Conclusions Intravenous Sufentanil in elderly patients the best background dose of 1.5g / h. [Keywords:] in elderly patients; sufentanil; intravenous analgesia Sufentanil synthesized in 1974, is a phenyl piperidine, N-4-substituted fentanyl derivatives, is the analgesic effect of opiates in most new high-fat-soluble analgesics. Clinical Research found that the analgesic effect of sufentanil morphine 1000 times, alfentanil 40 ~ 50 times, fentanyl 5 to 10 times. In recent years, both at home and abroad for many postoperative intravenous sufentanil PCA reports, using different doses, especially for elderly patients, still needs further observational studies, this stu