Esomeprazole triple therapy Hp-positive peptic ulcer clinical observation.docVIP

 PAGE \* MERGEFORMAT 6 Esomeprazole triple therapy Hp-positive peptic ulcer clinical observation [Abstract] Objective To observe the Cha Aisuo Merah zole triple therapy for Helicobacter pylori (Hp)-positive effect of peptic ulcer. Methods 80 cases of eligible patients were randomly divided into two groups, treatment group 40 cases, the application of metronidazole esomeprazole triple clarithromycin 1 week, followed by three weeks of esomeprazole therapy; the control group of 40 patients, Application of triple clarithromycin omeprazole metronidazole 1 week, followed by 3 weeks treatment Losec. Before treatment, treatment for 4 weeks after gastroscopy, and Hp inspections are conducted to evaluate efficacy. Results In the treatment group and control group, ulcer healing rates were 95.0% and 92.5%, no statistically significant difference between the two groups (Pamp;gt; 0.05); Hp eradication rates were 90.0% and 72.5%, statistically significant difference between the two groups (P amp;lt;0.05). Conclusion esomeprazole triple Hp infection in peptic ulcer can be used as the preferred therapy. [Keywords:] Helicobacter pylori peptic ulcer esomeprazole Peptic ulcer (peptic ulcer, PU) is a global common diseases, mainly referring to occurred in the stomach and duodenum, chronic ulcers, or gastric ulcer (GU) and duodenal ulcer (DU). GU and DU main reason is that the incidence of Helicobacter pylori (Hp) infection and gastric acid and pepsin digestion. Of Hp eradication of Hp-positive peptic ulcers must have reached a consensus, the standard doses of proton pump inhibitor (PPI) combined with metronidazole and clarithromycin for 1 week therapy has been recommended as first-line eradication of Hp the program [1]. By June 2006 to June 2008, using esomeprazole, clarithromycin and metronidazole triple therapy for peptic ulcer Hp-positive 40 cases and achieved better efficacy, these are as follows. 1 Data and methods 1.1 General Information Case inclusion criteria: (1) age