Evodia Decoction prevention of cisplatin induced vomiting the clinical observation of delayed.docVIP

 PAGE \* MERGEFORMAT 5 Evodia Decoction prevention of cisplatin induced vomiting the clinical observation of delayed [Abstract] Evodia Decoction prevention of cisplatin induced the clinical effect of delayed vomiting. [Method] 38 patients with malignant tumors, 19 cases were randomly divided into control and treatment group of 19 patients in the control group with granisetron in intravenous chemotherapy, the treatment group based on the above, while taking the medicine Evodia Decoction, after treatment. [results] the control group was 31.5% effective antiemetic treatment group was 68.4%, P lt;0.05. [Conclusion] Evodia Decoction on cisplatin induced delayed vomiting and has a good effect. [Keywords:] Evodia soup, vomiting, response to chemotherapy Chemotherapy in the process, often lead to varying degrees of nausea and vomiting, especially platinum drugs cisplatin is the most likely to cause vomiting of chemotherapy drugs. Clinically occurred within 24h of acute vomiting and vomiting is called, and will occur at 24h, and vomiting after chemotherapy is called delayed vomiting. now commonly used in clinical 5 HT3 receptor antagonists (eg granisetron better acute vomiting, but less effective against delayed vomiting. We use Granisetron medicine Evodia Decoction combined with cisplatin prevention of delayed chemotherapy-induced vomiting, and with a single agent for the randomized comparison of granisetron and achieved satisfactory results. 1 Materials and Methods 1.1 Clinical data Collection of our department from June 2005 to August 2007 38 patients with malignant tumor were randomly divided into treatment group of 19 patients in the control group of 19 patients. Which 22 males and 16 females. Aged 36 to 74 years, median age 52. including 12 cases of lung cancer, gastric cancer 10 cases, 6 cases of esophageal cancer, colon cancer, 5 cases of breast cancer in 5 cases. treatment options for DDP + NVB, DDP + Taxol, DDP + GEM, DDP + CF / 5 Fu, DDP + C