Faerie strong bones oral liquid on retinoic acid-induced osteoporosis the therapeutic effect of.docVIP

 PAGE \* MERGEFORMAT 8 Faerie strong bones oral liquid on retinoic acid-induced osteoporosis the therapeutic effect of Author: Wang Dongchun, Tan Aimin, Ma Ping, Liu Keywords: Faerie strong bones oral;,, osteoporosis;,, RA Abstract: Objective To observe the Faerie strong bones oral liquid on retinoic acid-induced osteoporosis therapeutic effect. Methods 70 mg / kg retinoic acid continuously fed 45 d, induced the formation of male rat model of osteoporosis. Modeling the success of the rats were randomly divided into strong bones oral high, medium and low-dose group and positive drug group, model group, a separate control group to begin delivery. 45 d after the administration of blood collected in serum separation determination of alkaline phosphatase (ALP), tartrate-resistant acid phosphatase (StrACP), isolated rat bilateral femur, femur bone parameters measured. Results Faerie strong bones oral liquid on serum ALP levels, StrACP levels, bone mineral density, bone mineral content were improvement. Conclusion Faerie strong bones oral liquid on retinoic acid-induced osteoporosis therapeutic effects. Keywords:: Faerie strong bones oral; osteoporosis; RA Effect of Xianlingqianggukoufuye on Osteoporosis Rats Induced by Retinoic Acid Abstract: ObjectiveTo study the effects of Xianlingqianggukoufuye (XLQGKFY) on osteoporosis rats induced by retinoic acid MethodsThe osteoporosis of rats was induced by administering 70 mg / kg retinoic acid for 45 days. Rats were randomly divided into 5 groups: osteoporosis (OP), OP Etidronate Disodiuml, OP XLQGKFY (high dose, middle dose, low dose), the others were control group, and treated with drugs. Double in vivo fluorochrome labeling was administered to all rats. At the end-point of study, the blood was collected to detect contents of ALP, ACP in serum, femur bone sections were cut for BMP analysis. ResultsXLQGKFY decreased the StrACP, increased StrACP and BMP. ConclusionXianlingqianggukoufuye has