Familial dilated cardiomyopathy incidence and pathogenesis of Research Progress.docVIP

 PAGE \* MERGEFORMAT 10 Familial dilated cardiomyopathy incidence and pathogenesis of Research Progress Keywords:: cardiac arrhythmia disease, cardiac hypertrophy Familial dilated cardiomyopathy (FDCM) the discovery of nearly 50 years. Family of common clinical enlargement of the heart, arrhythmia, ECG check QRS spill T wave abnormalities, pathological manifestations of myocardial fibrosis and residual cardiac hypertrophy. 60 years some scholars have explicitly put forward the familial cardiomyopathy, and thus distinguishes it from other specific cardiac lesions caused by enlargement of the heart. The incidence rate of 1 FDCM To date the incidence of relevant foreign FDCM result of the study varied, some quite different reasons there are at least three areas, first, dilated cardiomyopathy in different clinical manifestations of the severity of the illness has been mixed. Early in the disease, often no obvious symptoms, lower rate of treatment, many patients until the emergence of a more visible before diagnosis and treatment of heart failure. The second is the increased cardiac situation is more complex, in addition to a small number of patients with other causes confusion due to enlargement of the heart, the degree of enlargement of the heart in some patients is not obvious, and some family of growth with age in patients with dilated cardiomyopathy showed morphological characteristics. The third is to study the conditions vary, some prospective studies, that is, to a group suspected dilated cardiomyopathy patients and their immediate blood relatives one by one, history, physical examination, echocardiography and other tests, and follow-up observation, discovered Patients with family. Some retrospective analysis, that is known to other family members of patients, through the medical history review, questionnaires and other forms to be analyzed to confirm whether FDCM. Now some of the major studies abroad are summarized below. China Xu Jun et al [1] reported