Fried malt drug-containing serum αtransitional elements Bromocriptine high-performance liquid chromatography and quantitative analysis.docVIP

 PAGE \* MERGEFORMAT 11 Fried malt drug-containing serum αtransitional elements Bromocriptine high-performance liquid chromatography and quantitative analysis [Abstract] Objective To fry malt drug-containing serum α  Bromocriptine for qualitative and quantitative analysis. Methods fried malt ingredients known to contain α  Bromocriptine as a reference substance, by gavage feeding of rabbits in experimental animals served fried malt, high performance liquid chromatography comparison of experimental animals were fried rabbit serum containing malt , positive control drug bromocriptine drug-containing serum and blank serum non-high-performance liquid chromatography of the establishment of α  Bromocriptine quantitative detection methodology. Results α  Bromocriptine and scrambled malt-containing serum and serum components with bromocriptine peak part of the same, while the blank serum at the same retention time and the absence of the peak shape, HPLC method ultimately measured fried wheat-containing serum in α  Bromine Implicit stop content (0.070 2 ± 0.01) μ g / g. Conclusion rabbits fed by speculation malt, the blood has fried malt-derived α  Bromocriptine transitional elements, nature has not changed, the establishment of quantitative analysis of the composition of the methodological practices. [Keywords:] fried malt α Bromocriptine high-performance liquid chromatography Abstract: ObjectiveTo do quantitative and qualitative analysis for the α -Ergolactin in the stir-baked malt contained rabbit blood serum.MethodsTaking α  Ergolactin as reference, HPLC was used to compare rabbit stir-baked malt contained blood serum, Bromocriptine contained blood serum and blank blood serum.ResultsBoth the stir-baked malt contained blood serum and Bromocriptine contained blood serum had a part of the same peak in the HPLC chromatogram as α  Ergolactin reconstituent, obviously different with the blank blood serum. ConclusionAfter intragastric administra