Gui pain capsule attached to the anti-inflammatory analgesic effect of.docVIP

 PAGE \* MERGEFORMAT 11 Gui pain capsule attached to the anti-inflammatory analgesic effect of Authors: YUE Xing-for example, Ruan, Liu Ping, Wang Shu-Song 【Abstract】 Objective To study the capsule attached to Gui bone pain (FGC) of the anti-inflammatory analgesic effect. Methods were used anti-inflammatory experimental rat paw edema method, mouse peritoneal capillary permeability law and mouse granuloma hyperplasia; analgesic use of formaldehyde-induced experimental pain, hot plate and acetic acid writhing France. Results FGC 60 mg * kg-1, and 200 mg * kg-1 can significantly reduce the egg white-induced paw edema percentage. FGC 100 mg * kg-1, and 300 mg * kg-1 can effectively inhibit capillary permeability in mice, suggesting that the drug has anti-inflammatory effects. Analgesia experiments, FGC 20 mg * kg-1, and 60 mg * kg-1 can significantly reduce the formaldehyde-induced pain in rats carrying the full number of times, FGC 100 mg * kg-1, and 300 mg * kg-1 could significantly increase the hot-plate induced pain threshold, reduce the number of writhing; FGC 300 mg * kg-1 group also significantly prolong the incubation period of twisted body. Conclusion FGC has obvious anti-inflammatory and analgesic effect. Keywords: attached to Gui pain capsule; anti-inflammatory; analgesic Abstract: ObjectiveTo study the anti-inflammatory and analgesic effect of FuguiGutong Capsule (FGC). MethodsAnti-inflammatory effect of FGC was studied with the model of egg white induced swelling in rat paw and of dye exudation induced by acetic acid. Using the pain model in mice induced by acetic and hot plate, the analgesic effect of FGC was investigated.Results FGC (60,200 mg * kg-1) significantly reduced the degree of the swelling induced by egg white in rat, and FGC (100,300 mg * kg-1 ) inhibited the dye exudation induced by acetic acid in mice, which indicated its anti-inflammatory its effect. FGC (20,600. mg * kg-1) obviously decreased the number of r