Hepatitis varicella combination vaccine for measles aged humoral immune function.docVIP

 PAGE \* MERGEFORMAT 9 Hepatitis varicella combination vaccine for measles aged humoral immune function Of: Li Yinghua Guan Feng Zhao Hongguang Wang Qi Lin on behalf of Yu Cheng He Silver Abstract Objective To study the combined hepatitis A vaccine in elderly chickenpox measles humoral immunity. Methods chickenpox measles combined hepatitis A vaccine, hepatitis A vaccine, measles vaccine, varicella vaccine were injected old mice were antibody positive rate and antibody at different times the growth and decline. Seroconversion experimental results show that the combined vaccine and monovalent vaccines have the same good immunogenicity. Antibody test results, the combined hepatitis A vaccine produced antibodies, measles antibodies compared with the monovalent vaccine, with significant differences (P lt;0.05); varicella antibody compared with the monovalent vaccine, no significant differences, but the antibodies produced earlier in the unit price vaccine. Complement activity results, the combined vaccine and monovalent vaccine, compared with a significant difference (P lt;0.05). Conclusion The combined hepatitis A chickenpox vaccine measles virus antibody of the three has a positive synergistic effect, combined vaccine enhanced humoral immune function in aged mice was stronger than monovalent vaccines. Keywords: hepatitis varicella combination vaccine against measles; aged mice; humoral immune function Prevention of hepatitis A, measles, chicken pox 3 is the best way infectious diseases vaccination, the current vaccines are monovalent vaccine, hepatitis A domestic combined vaccine against measles, measles, varicella combination vaccine coverage 1,2, but at home and abroad varicella combination vaccine against measles is no hepatitis related reports. In this study, varicella combination vaccine of measles hepatitis in mice injected, through the detection of antibody titers were observed rise and fall of antibody to calculate positive rate and seru