Hyaluronic acid (HA) features and production of progress.docVIP

 PAGE \* MERGEFORMAT 8 Hyaluronic acid (HA) features and production of progress 【Abstract】 The linear structure of hyaluronic acid, super absorbent and how it combines with water, into a flexible and transparent membrane in soothing hydration to restore soft tissue and clinical aspects of Obstetrics and Gynecology the application of the more detailed exposition of the use of animal tissue as raw material extraction and use of bacteria such as Streptococcus zooepidemicus made a systematic summary of the fermentation. Keywords: hyaluronic acid; physiological function; application; production technology Hyaluronic acid (Hyaluronicacid referred to as HA), also known as hyaluronic acid, is a straight-chain high molecular weight polysaccharides. As early as 1934, Mey-er, and Palmer [1] the first time from bovine tissues isolated from the vitreous body hyaluronic acid and its sodium salt, after the hyaluronic acid and its anti-ions generated by the ion pair or salt collectively referred to as hyaluronan (HA ). It is made (1-3) -2 - acetamido -2 - deoxy-D-glucose (1-4)-DD-glucuronic acid disaccharide repeating unit composed of straight-chain mucopolysaccharide, and its molecular weight is generally 5 ~ 8 million, depending on the source and manufacturing methods may be taken. Hyaluronic acid found in connective tissue such as joints, vitreous, synovial fluid, umbilical cord, cartilage, skin, comb, A Tribe, and C hemolytic streptococci, and Wharton gel in order to meet a number of important functions such as toughness, as well as the support structure cell metabolic regulation. 1 HA physical and chemical properties and physiological functions HA has many natural polysaccharides common properties: white, amorphous solid, odorless and tasteless, there are strong hygroscopicity, insoluble in water, insoluble in organic solvents. However, in terms of compared to other mucopolysaccharide, HA has a unique nature, and with a volume of po