Hyperlipidemia and diabetes-related peripheral neuropathy study.docVIP

 PAGE \* MERGEFORMAT 7 Hyperlipidemia and diabetes-related peripheral neuropathy study [Abstract] Objective: To investigate the lipid metabolism disorder and diabetic peripheral neuropathy (diabetic peripheral neuropathy, DPN) relationship. Methods: Establishment of DPN lesions and diabetic patients without neuropathy group (NDPN), of which 84 patients DPN, NDPN 93 patients cases of the 177 patients with type 2 diabetes mellitus indicators of serum lipid test results were analyzed retrospectively. Results: DPN group than NDPN serum total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C) and apolipoprotein B (ApoB) were significantly higher (all P lt;0.05), insulin sensitivity index (HOMA-IR) DPN patients was significantly lower than NDNP group, the difference was statistically significant (P lt; 0.05). DPN group NDPN serum high density lipoprotein cholesterol (HDL-C) no significant difference (Pgt; 0.05. Conclusion: The lipid metabolism in type 2 diabetic patients with DPN are important risk factors, lipid metabolism may be involved in the development of diabetic neuropathy process. [Keywords:] diabetic neuropathy, lipid metabolism disorders For diabetes, lipid metabolism disorders in patients with diabetic cardiovascular risk factors of major events, this view has been reached. This study determined and compared peripheral neuropathy in type 2 diabetes and type 2 diabetes, non-lipid and peripheral neuropathy Other indicators of metabolic syndrome, of hyperlipidemia and other indicators of metabolic syndrome and diabetic neuropathy relevance for understanding the pathogenesis of diabetic neuropathy, diabetic neuropathy is a need to strengthen lipid-lowering therapy in patients with certain significance. 1 Subjects and methods 1.1 The study will be from June 2006 to February 2007 in our hospital Endocrine and Metabolic Diseases Division of hospitalized patients with type 2 diabetes (diabetes are in line with 1999 WHO