Injection of sodium aescinate a comprehensive analysis of adverse reactions.docVIP

 PAGE \* MERGEFORMAT 4 Injection of sodium aescinate a comprehensive analysis of adverse reactions [Abstract] Objective To study the injection of sodium aescinate caused by adverse reactions. Methods from 1998 to 2006 reported in the literature to summarize analysis. The results of sodium aescinate adverse reactions phlebitis, venous blood vessel contraction, fingers bruising, and skin necrosis, allergic reactions, allergic shock, kidney damage, liver damage, bradycardia, laryngeal edema, rhabdomyolysis, breathing difficulties. Conclusion medical and nursing staff should pay attention to injection of sodium aescinate adverse reactions to promote the rational use of medicines. [Keywords:] sodium aescinate adverse reactions Sodium aescinate Fearless from millet plants of Aesculus dry mature seeds extracted ester bond-containing triterpenoid saponin of the sodium salt. That the body has increased plasma concentrations of ACTH and cortisone, can promote blood vessel wall to increase the secretion of PGF2α , the body can eliminate free radicals, which play an anti-inflammatory, anti-leakage, improve venous tension, accelerate the venous flow, promote lymphatic flow to improve blood circulation and micro-circulation and the role of the protection of the vessel wall. Clinic for cerebral edema, swelling caused by trauma or surgery, but also in venous disorders. In the statement of adverse drug reactions expressed as follows: local injection site pain, swelling, occasional allergic reactions. However, in clinical applications, there are other adverse reactions caused by clinical staff should be extensive attention is now almost a few years after the literature review summarized as follows. 1 can cause phlebitis, venous blood vessel contraction Intravenous infusion of sodium aescinate, after infusion 3 ~ 5 d after the start of phlebitis, patients with drug sensitive or drug the same day symptoms. Intravenous infusion showed up along the 5 ~ 50 cm of the skin, dull