Insulin resistance in patients with type 2 diabetes and cognitive function between.docVIP

 PAGE \* MERGEFORMAT 13 Insulin resistance in patients with type 2 diabetes and cognitive function between Study: Red Fang Lu is Tang Wei Xiao Zheng Chen Min Zhu Yongfang [Abstract] Objective To investigate insulin resistance in patients with type 2 diabetes (IR) relationship with cognitive function. Methods 89 patients with type 2 diabetes survey of cognitive function, and homeostasis model insulin resistance index (HOMA IR) assessment of IR degree. to HOMA IR value of 3.61 on the 75 percentile as the cutoff point, divided into 2 groups, comparing HOMA IRgt; = 3.61 group with HOMA IR lt;3.61 between groups waist circumference, body mass index (BMI), blood lipids, blood pressure, urinary albumin / creatinine ratio (UALB / Cr), TSH (TSH) and other aspects of cognitive function. The results of the two groups waist circumference, BMI, triglycerides (TG), cholesterol / high density lipoprotein (TC / HDL C ), UALB / Cr, TSH was significant difference; two groups in MMSE scores, memory (including immediate memory and short memory), executive function and language understanding and so there was a significant difference; HOMA IR and waist circumference, TG, UALB / Cr were positively correlated with the auditory verbal memory latency negative correlation. Conclusions and further increased the IR of patients with type 2 diabetes cognitive damage; normal TSH levels increased within the increased IR, and type 2 IR-induced diabetic cognitive impairment had significant role in promoting. [Keywords:] Insulin resistance; cognition; diabetes mellitus; 2 With the population aging, diabetes and Alzheimer’s (AD) is increasing. Insulin and insulin resistance (IR) relationship between the two may play an important role (1). The current study suggests that, IR can be caused the decline of cognitive function, particularly the decline in memory ability and the opportunity to increase the risk of AD (2), but the IR in type 2 diabetic patients with different degree of cogniti